OBJECTIVES To study the contact allergenic activities of trichloroethylene (TCE) and its three metabolites trichloroacetic acid, trichloroethanol and chloral hydrate. METHODS A modified guinea pig maximization test (GPMT) was adopted. The skin sensitization (edema and erythema) was observed in trichloroethylene, trichloroacetic acid, trichloroethanol, chloral hydrate and 2,4-dinitrochlorobenz...

July. The day following he was admitted into hospital as an in-patient. Symptoms on Admission.?Extreme rigidity of muscles of neck, jaws, and back; abdomen and extremities also slightly affected; can barely open his mouth; bowels costive; pulse hard and quick ; tongue white and dry. Complains of great thirst, but can with difficulty swallow. Temperature of body normal. Tetanic spasms follow at ...

Efficacy of medetomidine HCl anesthesia was evaluated in 48 horses, divided randomly into six groups (n=8). Initially, propofol, ketamine and chloral hydrate were evaluated individually as sole anesthetic drugs in groups A C and E, respectively. Later on the efficacy of medetomidine HCl as pre-anesthetic was assessed by using it in combination with other drugs. In group B, medetomidine HCl was ...

BACKGROUND AND AIMS The colons of patients with pneumatosis cystoides coli produce excessive H2. Exposure to alkyl halides could explain this. Six consecutive patients who had pneumatosis cystoides coli while taking chloral hydrate (1-5+ g/day) are reported. Patients 2 and 3 were investigated after they had ceased chloral hydrate treatment. One produced methane, the other did not. (Pneumatosis ...

background: chloral hydrate (ch) is a sedative agent that is widely used in infants and children for several decades. the purpose of this study was to evaluate the safety and efficacy of ch before general anesthesia in pediatric population undergoing eye examination. methods: 165 pediatric patients with retinal tumor were examined from december 2014 to may 2015. 158 (95.7%) children were sedate...

BACKGROUND Living donor liver transplantation (LDLT) patients run the risk of developing acute kidney injury (AKI) and subsequent chronic kidney disease, affecting morbidity and mortality. Sevoflurane has anti-inflammation properties, and renal ischemia/reperfusion under sevoflurane anesthesia resulted in drastic improvements in renal function. Extrahepatic metabolism of sevoflurane has been re...

A survey of 325 American Board of Pedodontics Diplomates was conducted to determine the use of chloral hydrate and other sedative medications in treating young, uncooperative children needing extensive operative procedures. Seventy-one per cent of the respondents returned usable surveys. Seventyeight per cent of the Diplomates indicated they use sedative agents for these patients. However, the ...