background chronic hepatitis b virus (hbv) infection is a multifactorial disease that can result in serious clinical complications. host genetic background especially the genes that encode immunologic factors like inf-γ and its receptor (ifn-γ r) are critical in the pathogenesis of infection. materials and methods genomic dna from peripheral blood samples of 200 chronically hbv infected patient...

background and objective: given the widespread use of paraffin in the treatment of constipation in chil-dren and the possibility of long duration of drug use and the risk of drug leakage, the risk of urinary infection in these patients is considerable. the aim of this study was to determine the association between leakage of paraf-fin and the presence or exacerbation of the urinary infection an...

Background: The most common sexually transmitted diseases and the economic and social health problem throughout the world. However, vaccine coverage and antibiotic therapy and the development of programs to prevent and control major causes of acute and chronic diseases, pregnancy complications and infertility remains. Acute and chronic systemic viral infections can lead to infertility and perma...

conclusions our study showed no correlation between rs12979860 and rs8099917 snps and chronic hbv infection. further studies, with larger sample sizes and different ethnicities, are necessary to validate our findings. objectives this study was carried-out to investigate the association of ifnl3 gene polymorphisms (rs12979860 and rs8099917) with hbv susceptibility, in chronic hbv-infected patien...

a hepatitis b virus (hbv) infection is a global public health problem. in endemic areas, hbv infection occurs mainly during infancy and early childhood, with mother to child transmission (mtct) accounting for approximately half of the transmission routes of chronic hbv infections. prevention of mtct is an essential step in reducing the global burden of chronic hbv. natal transmission accounts f...

conclusions trim22 gene ring domain -364t/c polymorphism is associated with chronic hbv infection in chinese han population. results 243 (31.76%) of 765 chinese han patients showed genetic variation in the trim22 gene. trim22 snps were mainly in ring area -364t/c site, accounting for 98.35% of the population. there were no significant differences (p > 0.05) in the ring domain -364t/c snp and al...

background and aims: chronic hbv infection is one of the most common viral infections in worldwide which many factors such as genetic factors are involved in pathogenesis of disease. gamma interferon (ifn-γ) and its receptor (infgr) play a critical role in the immune response to hbv infection. single nucleotide polymorphisms (snps) are effective on level of gene expression, the aim of this stud...