BACKGROUND Although invasive pulmonary aspergillosis (IPA) is more prevalent in immunocompromised patients, critical care clinicians need to be aware of the occurrence of IPA in the nontraditional host, such as a patient with chronic lung disease. The purpose of this study was to describe the IPA patient with chronic lung disease and compare the data with that of immunocompromised patients. M...

Background: In this study, we aimed to assess the prevalence of comorbidities in the confirmed COVID-19 patients. Thismight help showing which comorbidity might pose the patients at risk of more severe symptoms.Methods: We searched all relevant databases on April 7th, 2020 using the keywords (“novel coronavirus” OR COVID-19OR SARS-CoV-2 OR Coronavirus) AND (comorbidities OR cl...

BACKGROUND The oxidant/antioxidant balance in lung tissue is hypothesised to contribute to the risk of chronic obstructive pulmonary disease (COPD). Observational studies consistently report higher antioxidant status associated with lower COPD risk, but few randomised studies have been reported. METHODS A post hoc analysis of 38,597 women without chronic lung disease at baseline was conducted...

Background: Primary graft dysfunction (PGD) and acute kidney injury (AKI) are major early complications of lung transplantation associated with increased mortality. Lung after PGD can contribute to renal dysfunction; however, the association between AKI severity has not been thoroughly investigated. We analyzed grading staging, impact on subsequent changes chronic disease (CKD), including glome...

Legionella pneumophila is a thin, aerobic, Gram-negative, pathogenic bacillus and the leading cause of Legionnaires’ disease (LD) in human, especially those with high risk conditions including immune system disorders or chronic lung diseases. The mortality rate of LD has been reported to be 60% or higher in inappropriately treated cases. Investigating the prevalence of L. pneumophila and identi...

Background- Chronic Obstructive Pulmonary disease (COPD) as defined by Global Initiative for Lung Disease (GOLD) is a common preventable and treatable disease, characterized persistent airflow limitation that usually progressive associated with an enhanced chronic inflammatory response in the airways lung to noxious particles or gases. Objectives-To evaluate outcome of NIV terms ofTime reversio...

Cigarette smoking is growing and nicotine is considered as the most adverse agent in the cigarette smoking. Nicotine is an alkaloid and forms 90% of alkaloids of cigarette. Nicotine is accountable for creating disorders and cancers such as lung cancer, heart disease and chronic lung disease. Nicotine can be considered as an autophagy and apoptosis inducer which can either directly or indirectly...