BACKGROUND Premature ejaculation is one of the most problems in clinical practice. The association between varicocele and premature ejaculation was poorly understood. The effects of varicocelectomy on premature ejaculation in varicocele patient was studied. OBJECTIVES The aim of this study was to determine the impacts of varicocelectomy on patients with both premature ejaculation and varicoce...

Premature ejaculation (PE) is a common sexual dysfunction in men that is characterized by a short time to ejaculation, and a lack of control over ejaculation, and is associated with distress for men and their partners. Lack of knowledge about the aetiology of PE and lack of approved treatments might contribute to its under-diagnosis and under-treatment. The organic factors involved in PE are no...

Introduction. Premature ejaculation (PE) is the second most common male sexual dysfunction with a significant negative impact on quality of life. To date, there no satisfactory treatment for PE. Surgical methods are based reducing sensitivity glans penis by various methods, main which selective dorsal neurotomy (SDN). Recently, have been developed temporary demyelination nerve using cryoablatio...

This article reviews the psychological theories and treatment approaches to premature ejaculation. It also describes the potential negative psychological effect of this condition on the man and his partner. Recommendations and guidelines for providing individual and conjoint treatment with the partner are discussed as is the role of combined pharmacological and psychological intervention. The l...

Premature ejaculation has generally been considered a psychosexual disorder with psychogenic aetiology. Although still mainly treated by behavioural therapy, in recent years double-blind studies have indicated the beneficial effects of some of the serotonergic antidepressants (SSRIs) in delaying ejaculation. We describe here the neurophysiology and the peripheral neuroanatomy of ejaculation and...

The ejaculatory response and the 5-hydroxytryptamine (5-HT) behavioural syndrome induced by 5-methoxy-N,N-dimethyltryptamine (5-MeODMT) (3 mg kg-1 i.p.) were studied following acute and repeated treatment of rats with the selective uptake inhibitors of 5-HT, fluoxetine, zimeldine, alaproclate, and citalopram. The oral doses used were based on the respective ED50 values for uptake inhibition. Ac...

conclusions the results of the study show that tadalafil can increase the mean ielt and can be used for treatment of premature ejaculation in combination with paroxetine. results the mean age of patients in groups a and b were 33 ± 9.6 and 31.2 ± 9.3 years, respectively (p = 0.368). the mean number of intercourses were 1.08 ± 0.6 and 1.12 ± 0.6 per week in groups a and b, respectively (p = 0.79...