The use of a multileaf collimator in the dynamic mode to perform intensity modulated radiotherapy became a reality at our institution in 1995. Unlike treatment with static fields using a multileaf collimator, there are significant dosimetric issues which must be assessed before dynamic therapy can be implemented. We have performed a series of calculations and measurements to quantify head scatt...

In October 2009, a quad, mini-beam collimator was implemented at GM/CA CAT that allowed users to select between a 5, 10, or 20 micron mini-beam or a 300 micron scatter guard for macromolecular crystallography [1]. Initial alignment of each pinhole to the optical axis of each path through the mini-beam collimator is performed under an optical microscope using an alignment jig. Next, the pre-alig...

PURPOSE AND METHODS The noninvasive microsphere (NIMS) method quantifies cerebral blood flow with N-isopropyl-p-[123I]-iodoamphetamine (123I-IMP) without blood sampling of a patient, but when a fan beam collimator is used for collecting raw data in single photon emission computed tomography (SPECT), the procedure is complicated because we have to change the collimator. In phantom and clinical s...

BACKGROUND Scintillation camera imaging is used for treatment planning and post-treatment dosimetry in liver radioembolization (RE). In yttrium-90 (90Y) RE, scintigraphic images of technetium-99m (99mTc) are used for treatment planning, while 90Y Bremsstrahlung images are used for post-treatment dosimetry. In holmium-166 (166Ho) RE, scintigraphic images of 166Ho can be used for both treatment p...

Background. Although heart-to-mediastinum (H/M) ratio in a planner image has been used for practical quantification for I-metaiodobenzylguanidine (MIBG) imaging, standardization of the parameter is not yet established. We hypothesized that the value of H/M can be standardized to the various types of camera-collimator combinations. Methods and Results. Standard phantoms consisting of the heart, ...

The high beam intensities in the next linear collider can damage the collimation system jaws if a failure of the electronic machine protection system allows the acceleration of a mis-launched pulse. We are developing a prototype collimator that will allow a new jaw surface to be moved into place after beam damage. We are also developing a prototype collimator based on continuously reforming the...

INTRODUCTION Lymphoscintigraphy is an important part of sentinel node mapping in breast cancer patients. Sometimes star shaped artefacts due to septal penetration can be problematic during imaging. In the current study, we evaluated the possibility of high energy (HE) collimators use for lymphoscintigraphy. PATIENTS AND METHODS Twenty patients with early breast carcinoma were included. Thirty...

The Relativistic Heavy Ion Collider (RHIC) will experience increasing longitudinal and transverse heavy ion emittances, mostly due to intra-beam scattering (IBS). The experiments in RHIC are expected to not only have reduced luminosi-ties due to IBS but also an unwanted beam halo. Primary betatron collimators will be used to remove the large amplitude particles. The efficiency of the primary co...