Although a high proportion of marriages in Asia are consanguineous (i.e. contracted between close biological relatives), with some notable exceptions, there is a death of demographic and anthropological literature on the association between consanguinity and fertility. This paper presents an overview of the prevalence of consanguineous marriages in selected South and Southeast Asian countries, ...

Many different types of genetic disorders are noted to be prevalent among consanguineous progeny. Although the most common type of consanguineous union in all major societies is between first cousins, the importance of customary influences is apparent from variations in the specific types of first-cousin marriages contracted. Epidemiological data for the prevalence of whistling-face syndrome (W...

Deafness is a complete or partial loss of hearing. In Pakistan, the prevalence of this order is high as compared to the other countries because of frequent consanguineous marriages in Pakistan. During present study, DFNB49 was mapped in two unrelated consanguineous families having multiple affected individuals. The maximum LOD score was found 4.71 and 2.74 for PKDF1069 & PKDF751 respectively. T...

Consanguineous marriages have been common throughout human history, and remain so even today in many parts of the world. Many Arab countries display some highest rates consanguinity and, specifically, first cousin which may encompass 25 to 30 percent all marriages. The effects inbreeding on reproductive outcome extensively studied. It used be generally believed that contributed increased mortal...

OBJECTIVE With 20-30% of all marriages occurring between first cousins, increasing attention in Jordan is now given to role of consanguinity in the occurrence of genetic diseases. The objective of this study is to define the specific categories of genetic disorders associated with consanguineous marriages. METHODS Etiological categories and consanguinity rates were studied among 623 families ...

These selected respondents reported a very high incidence of first-cousin marriages in their families. A smaller proportion of marriages were with more distant cousins, but Pearson remarked that second and third cousins in these families were also often related in more than one line. He lumped them all together and concluded that 'consanguineous marriages in the professional classes probably oc...

The biraderi (brotherhood) is a long-established, widely prevalent dimension of social stratification in Pakistani communities worldwide. Alongside consanguinity, it offers a route for cementing social solidarities and so has strong socio-biological significance. A detailed breakdown of biraderi affiliation among participants in an ongoing birth cohort study in the northern English city of Brad...

Consanguineous marriages have been practiced since the early existence of modern humans. Until now consanguinity is widely practiced in several global communities with variable rates depending on religion, culture, and geography. Arab populations have a long tradition of consanguinity due to socio-cultural factors. Many Arab countries display some of the highest rates of consanguineous marriage...