BACKGROUND Rates of nonadherence to aromatase inhibitors (AIs) among Medicare beneficiaries with hormone receptor-positive early breast cancer are high. Out-of-pocket drug costs appear to be an important contributor to this and may be addressed by eliminating copayments and other forms of patient cost sharing. The authors estimated the incremental cost-effectiveness of providing Medicare benefi...

Background & Aim: Cataract disease is among the conditions that impose a substantial economic cost on countries every year due to their high prevalence rate. The prevalence of this disease has caused significant direct and indirect costs. This study aimed to estimate the economic burden caused by the costs of the cataract disease. Materials and Methods: This descriptive, analytical, and cross-...

The progressive deterioration associated with Alzheimer's disease (AD) results in high economic cost to the patients, caregivers, and the society as a whole. Cost-of-AD studies conducted over the last decade have produced discrepant results, mainly as a consequence of the different methodologies employed. The present review is an attempt to present the methodology of the cost studies in AD and ...

The Disease Control Priorities (DCP) project has substantially influenced national and global health priorities since 1993. DCP’s basic framework involves identification of disease burdens based on premature deaths and disability and application of the most cost-effective interventions to the largest burdens, taking into account local feasibility. The future impact of DCP will need to take into...

OBJECTIVE The general goal of this research was to determine the effectiveness of a home follow-up program in order to acquire guidance in how to plan the future structure and contents of post-myocardial infarction (MI) patients' care and rehabilitation. The specific aim of this study was to evaluate the cost-effectiveness of the program in reducing the rate of rehospitalization of first-time p...

In the absence of a cure, the primary goals in managing Parkinson's disease (PD) are to preserve functionality and health-related quality of life (HRQoL). Current therapeutic strategies for PD include symptomatic treatment and are primarily focused on replacing dopamine in the brain. Dopamine agonists can be used as an alternative initial levodopa therapy, to delay the onset of motor complicati...

Many clinical practice guidelines fail to account for the preferences of the individual patient. Approaches that seek to include the preferences of the individual patient in the decision-making process (e.g., interactive videodisks for patient education), however, may incur substantial incremental costs. Developers of clinical practice guidelines must therefore determine whether it is appropria...

To examine the relative cost-effectiveness of single versus multiple patient education strategies to reduce hypertension, we assigned patients to seven intervention groups and to a usual-care control group using a randomized factorial design. We compared cost-effectiveness measures for single, double, and triple combinations of (a) a clinic exit interview with patients to clarify their medical ...

background: myocardial infarction (mi) occurs due to heart muscle death that costs like human life, which is higher than the treatment costs. this study aimed to present an mi prediction model using classification data mining methods, which consider the imbalance nature of the problem. methods: we enrolled 455 healthy and 295 myocardial infarction cases of visitors to shahid madani specialized ...