Collective decision-making failures are often attributed to group members’ unwillingness to express unpopular opinions, and incident investigations frequently name lack of dissent as a causal factor (Sunstein, 2006). The investigation following the Columbia space-shuttle explosion, for instance, cited a culture at the National Aeronautics and Space Administration in which ‘‘it is difficult for ...

A Phase I dose-escalation study using 90Y-CYT-356 monoclonal antibody was performed in 12 patients with hormone-refractory prostate carcinoma. Biodistribution studies using 111In-CYT-356 were performed 1 week before 90Y-CYT-356 administration. Of the 12 patients, 58% had at least one site of disease imaged after administration of 111In-CYT-356. The dose of 90Y ranged from 1.83-12 mCi/m2. Both 1...

Binding of native cyt c to L-PG micelles leads to a partially unfolded conformation of cyt c. This micelle-bound state has no stable tertiary structure, but remains as alpha-helical as native cyt c in solution. In contrast, binding of the acid-unfolded cyt c to L-PG micelles induces folding of the polypeptide, resulting in a similar helical state to that originated from the binding of native cy...

compared to other methods of vaccine production, (e.g. culture flask and bioreactor system), the roller culture method for producing rabies vaccine is simpler, and the equipment easier to install and maintain, and also in the event of contamination of one roller, the entire batch need not be discarded. this system provides a much larger surface area than the culture flask, and also ensures a mu...

Packers have long been a valuable tool in the toolbox of offensive users for evading the detection capabilities of signature-based antivirus engines. However, selecting the packer that results in the most effective evasion of antivirus engines may not be a trivial task due to diversity in the capabilities of both antivirus and packers. In this paper, we propose the creation of an online automat...