background: oral lichen planus (olp) has been classified as a pre-malignant condition. matrix metalloproteinase-13 (mmp-13) or collagenase-3 may play a key role in cancer development. the aim of this study was to compare serum and saliva mmp-13 between patients with oral lichen planus (olp) and oral squamous cell carcinoma (oscc).   methods : this cross sectional study was performed on 30 patie...

the water-distilled essential oil from dried aerial parts of achillea tenuifolia lam. was analysed by gc and cg/ms. 48 components were characterized representing 88% of the total oil. camphor (18%), 1,8-cineole + limonene (9%) and spathulenol (7%) were the major constituents of the oil obtained in a yield of 0.23%.

the genus tanacetum is one of the most important medicinal plants that contains 26 species in iran, 12 of them are endemic. this paper reports the essential oil composition of  tanacetum angulatum willd. tanacetum canacens dc. and tanacetum pinnatum boiss. growing wild in iran. plant flowers and leaves were collected from different locations of north- west of iran. samples were hydro-distilled ...

results aβ (1-42) stimulated the production of the proinflammatory cytokines il6, il1β, tnfα, and il18 in both the primary microglia cell culture and the b92 cell line. both the raav-il4 construct and the ril-4 protein were found to inhibit production of the most important aβ (1-42)-induced proinflammatory cytokine mrnas in the two types of cells with different patterns. conclusions it seems th...

introduction: recently, due to the special characteristics of 166ho and chitosan, 166ho-chitosan complex was developed for treatment of tumors such as hepatocellular carcinoma. this complex has been lately prepared with high radiochemical purity in our lab. the preclinical studies of the complex however should be performed to evaluate the tracer concentration in target and normal tissues before...

background and purpose: shiraz university of medical sciences as one of the oldest and largest universities of medicine in iran with 50 years history has more than 450 faculty members and 5000 students. this study is an attempt to find out the level of job satisfaction among shiraz university of medical sciences’ faculty members. methods: in midterm of 2003-2004, data on job satisfaction level ...

background: variations in cytotoxic t lymphocyte antigen-4 (ctla-4) affect the expression and function of this protein. objective: we aimed to investigate the association of +49 a/g (rs231775), +1822 c/t (rs231779) and +6230 a/g (ct60, rs3087243) genetic variations, as well as the merged haplotypes in ctla-4 gene with susceptibility to, or progression of head and neck cancer. methods: eighty pa...

about 50% of all patients affected by crc develop liver metastases. surgery remains the only potentially curative strategy, but is impossible in the majority of patients. for non-resectable patients, two options are available: local treatment strategies (radiofrequency ablation and cryosurgery: alone or in combination with surgery) and chemotherapy. high rates of objective response achieved wit...