Purpose: To investigate the effect of quaternary amines on myocardial cells a rat model cardiac arrest, with respect to energy generation potential and oxygen free radicals.
 Methods: Forty-five Sprague-Dawley (SD) rats were assigned sham, amine groups (each 15 rats). After their corresponding treatments, lectrocardiogram (ECG) monitoring in three at various time periods was carried out. S...

To explore the protective effect of sesame seed oil (SSO) extracted from Til-06 variety in Sprague-Dawley male rats against management hypercholesterolemia, current two-phase study was conducted. In first phase, taken out seeds (Til-06) and physicochemical analysis carried to find content following by evaluation quality attributes oil. second efficacy check hyperlipidemic activity Randomly dist...

Injectable long-acting cabotegravir (CAB LA) is effective and safe for pre-exposure HIV prophylaxis. It recently approved clinical use in those at high risk of contracting HIV. However, injections are invasive access to trained healthcare personnel administer CAB LA can be limited, especially low-income countries (LICs). Herein, the first time, development a bilayer microarray patch (MAP) with ...

Background/Aim: Our understanding of cancer risk from neutron exposure is limited. We aimed to reveal the characteristics mammary carcinomas induced by neutrons. Materials and Methods: Mammary obtained female Sprague-Dawley rats irradiated at 7 weeks age with 0.97 Gy neutrons or 4 ?-rays non-irradiated were classified into luminal non-luminal subtypes immunohistochemistry. Their mutational land...

Background: This study used an experimental posttest-only control group design that involved white rats of the Sprague Dawley strain.
 Methods: The samples were 8-week-old rats, weighing 250–350 grams male sex. was conducted on five groups with a total seven per group.
 Results: mean value osteocytes in 00.00 ± and ALSR it 87.14 44.85. osteoblasts 50.06 5.76 283.63 22.86. showed there...

Previous work from our laboratories has shown that juvenile Fischer 344 (F344) rats are less playful than other strains and also appear to be compromised in dopamine (DA) functioning. To determine whether the dysfunctional play in this strain is associated with deficits in the handling and delivery of vesicular DA, the following experiments assessed the extent to which F344 rats are differentia...

Background: Areca nut (Areca catechu Linn.) is the seed of fruit oriental palm that commonly used among Southeast Asian communities. Chrysanthemum (Dendrathema grandiflora) a flowering plant originating from East Asia and dominantly grows in China. Both these plants have strong antioxidant activities. To investigate m...

Due to a large number of mutations in the spike protein and immune escape, Omicron variant (B.1.1.529) has become predominant concern (VOC) strain. To prevent disease, we developed candidate inactivated vaccine (Omicron COVID-19 Vaccine (Vero Cell), Inactivated). evaluate safety vaccine, tested repeat-dose toxicity Sprague-Dawley (SD) rats. The doses were administered randomly three groups: phy...