celiac disease is the inability of the small intestine to tolerate some cereal prolamin with sequence specific oligopeptide. wheat gliadin, rye secalins and barley hordenine are the main proteins involved in the disease mechanisms and may provoke an inflammatory process to damage the small intestine. there are different methods to overcome the problems for such patients one of them is using glu...

background: breast cancer arising in young patients (≤ 40 years) is being considered as a distinct clinical entity with more aggressive tumor features and poorer survival. our aim was to assess the impact of age on survival among a large group of iranian women diagnosed with breast cancer. methods: in a cross-sectional study, demographic and clinicopathological characteristics of patients with ...

In this paper, we propose a multi-patch model to study the effects of population dispersal on the spatial spread of malaria between patches. The basic reproduction number [Formula: see text] is derived and it is shown that the disease-free equilibrium is locally asymptotically stable if [Formula: see text] and unstable if [Formula: see text]. Bounds on the disease-free equilibrium and [Formula:...

background: celiac disease (cd) is an immune mediated condition that leads to small bowel atrophy that resolves with a gluten free diet (gfd). extra-intestinal manifestations of cd include hypertransaminasemia. in this study, the effects of a gfd on hypertransaminasemia in patients with newly diagnosed cd were studied. methods: ninety eight new diagnosed consecutive patients with cd 40 males an...

background: vitiligo is an acquired, idiopathic disorder characterized by circumscribed depigmented macules and patches. the exact etiology and pathogenesis of vitiligo is not clear. many theories have been presented regarding this subject among them aautoimmune theory is the most important one. the association of vitiligo with other autoimmune disorders has been reported, but the relationship ...

tolerable gluten thresholds in gluten free products have long been debated together with issues of cross contamination of gluten free cereals during the milling process. it is well established that a totally gluten free diet is virtually impossible owing to the presence of traces of gluten. it is estimated that daily consumption of gluten from contaminated gluten free foods is in the range of 5...

An SIRS epidemic model incorporating media coverage with time delay is proposed. The positivity and boundedness are studied firstly. The locally asymptotical stability of the disease-free equilibrium and endemic equilibrium is studied in succession. And then, the conditions on which periodic orbits bifurcate are given. Furthermore, we show that the local Hopf bifurcation implies the global Hopf...

We will study a mathematical model on the human immunodeficiency virus (HIV) infection in the presence of combination therapy that includes within-host infectious dynamics in the context of disease spread in vivo. The deterministic model requires us to analyze asymptotic stability of two distinct steady states, disease-free and endemic equilibria. Previous results have focused on investigating ...

In this paper, we studied the global dynamics of a SEIR epidemic model in which the latent and immune state were infective. The basic reproductive rate, R0, is derived. If R0 6 1, the disease-free equilibrium is globally stable and the disease always dies out. If R0 > 1, there exists a unique endemic equilibrium which is locally stable. Furthermore, we proved the global stability of the unique ...

In this paper, we establish a discrete-time analog for coupled within-host and between-host systems for an environmentally driven infectious disease with fast and slow two time scales by using the non-standard finite difference scheme. The system is divided into a fast time system and a slow time system by using the idea of limit equations. For the fast system, the positivity and boundedness of...