Chromatin immunoprecipitation and sequencing (ChIP-seq) provides a static snap-shot of DNA-associated proteins which fails to reflect the dynamics of the DNA-bound proteome. Now, Catic and co-workers combine ubiquitin ChIP-seq and proteasome inhibitors to map sites of DNA-associated protein degradation on a genome-wide scale. They identify an ubiquitin ligase which targets a transcriptional rep...

siahe-e-samarghandi is one of the most important cultivars of grapevine (vitis vinifera) in fars province. some problems of this cultivar are its sparse clusters with small berries and berries that are in different stages of growth. foliar application of urea, zinc sulfate, boric acid 4, 3 and 1gl-1, respectively as well as sodium molybdate at the concentrations of 0, 0.5, 1 and 1.5 gl-1 were a...

Bioinformatics applies unbiased approaches to develop statistically-robust insight into health and disease. At the global, or "20,000 foot" view bioinformatic analyses of vitamin D receptor (NR1I1/VDR) signaling can measure where the VDR gene or protein exerts a genome-wide significant impact on biology; VDR is significantly implicated in bone biology and immune systems, but not in cancer. With...

Split-hand/split-foot malformation is a rare limb malformation with median clefts of the hands and feet and aplasia/hypoplasia of the phalanges, metacarpals and metatarsals. When present as an isolated anomaly, it is usually inherited as an autosomal dominant form We report a case of autosomal dominant inheritance and discuss the antenatal diagnosis, genetic counseling and treatment for the mal...

For more efficient organizing, browsing, and retrieving digital video content, it is important to extract video structure information at both scene and shot levels. This paper presents an effective approach to video scene segmentation based on a pseudo-object-based shot correlation analysis. A new measure of the semantic correlation of consecutive shots based on dominant color grouping and trac...