Synchronous bilateral male breast cancer is a very rare entity and invasive lobular carcinoma is less common in male breast cancer (MBC) than in female breast cancer (FBC). A 51-year-old man presented with a palpable mass in the left breast was finally diagnosed synchronous bilateral MBC, one an invasive lobular carcinoma and the other an invasive ductal carcinoma. It remains a matter of debate...

OBJECTIVE Cascades that include β-catenin that has a function in adhesion and interaction with tumor suppressor genes such as APC have important roles in many neoplasms. The aim of the current study was to confirm the effect of the β-catenin pathway in breast tumor carcinogenesis and invasion. MATERIAL AND METHOD Polyclonal rabbit β-catenin antibody was applied to 52 cases of infiltrative duc...

We studied outcomes of 147 patients with stage I/II grade 1 (32 pure tubular, 115 ductal) carcinoma treated with breast-conserving therapy to evaluate the prognostic usefulness of standard and recently proposed revised criteria for tubular (tubularity percentage [proportion of neoplastic cells adjacent to open lumens], nuclear grade, and mitoses) and ductal carcinoma. Carcinomas with less than ...

We evaluated the clinicopathological features and prognosis of 29 cases of prostate ductal carcinoma was considered to be an aggressive subtype of prostate acinar carcinoma. We selected 29 cases who were diagnosed prostate ductal carcinoma and had a radical prostatectomy (RP). The acinar group (n = 116) was selected among 3,980 patients who underwent a prostatectomy. The acinar group was matche...

Ductal carcinoma in situ (DCIS) is a breast (BC) consisting of malignant cells the ductal lumen without invasion beyond epithelial membrane. The article presents rare clinical case combined course chronic mastitis and 47-year-old female patient who was diagnosed with during instrumental examination, only after trepan biopsy subsequent histological intraductal cancer verified. This may indicate ...

INTRODUCTION Invasive ductal and lobular carcinomas represent 67.9% and 6.3% of breast carcinoma, respectively. Metastatic breast cancer typically involves the lungs, bones, brain, and liver. Studies have shown differing patterns of metastatic spread between ductal and lobular carcinoma. Lobular carcinoma is more likely to metastasise to the gastrointestinal tract. CASE PRESENTATION We report...

BACKGROUND Resistance to human epidermal growth factor receptor-2 (HER2)-targeted therapies is common, and results in treatment failure and new tumor progression. C35 is over-expressed in many invasive breast cancer endogenously, and functions as an oncogene in breast cancer cell lines. METHODS The current study aims to investigate effects of C35 on cell viability and migration of HER2-positi...

Invasive ductal carcinoma and ductal carcinoma in situ account for about 85% of breast cancers. Unusual breast neoplasms may be broadly divided into invasive lobular carcinoma, well-differentiated subtypes of invasive ductal carcinoma, cancers of stromal origin, and metastatic neoplasms. Clues are often present in imaging characteristics, patient demographics, and/or clinical features that may ...

background : invasive ductal carcinoma is one of the most common type of tumors in females, constituting a single large group of breast cancers. there are various prognostic factors, of which tumor grade, size and axillary lymph node metastasis are among the important ones. fine needle aspiration cytology is a commonly used diagnostic technique in the initial evaluation of breast lumps. in the ...