OBJECTIVES Anticarbamylated protein (anti-CarP) antibodies are a novel family of autoantibodies recently identified in patients with inflammatory arthritis. The aim of this study was to investigate their association with long-term outcomes of disability and disease activity over 20 years' follow-up in a cohort of patients with inflammatory polyarthritis (IP). METHODS Norfolk Arthritis Registe...

BACKGROUND Utility scores are used to estimate Quality Adjusted Life Years (QALYs), applied in determining the cost-effectiveness of health care interventions. In studies where no preference based measures are collected, indirect methods have been developed to estimate utilities from clinical instruments. The aim of this study was to evaluate a published method of estimating the EuroQol-5D (EQ-...

Rapid urbanisation, the interconnection of economies and growing dependence on technology makes modern society increasingly vulnerable to natural disasters. In case of earthquakes, the mitigation of seismic risk in urban and industrial area can be effectively accomplished by Earthquake Early Warning systems (EEWS), which performs real-time event detection and characterization, issues rapid aler...

Effective project management requires reliable knowledge of cash required in different stages of project life cycle. Getting this knowledge is highly dependent on sophisticated consideration of project environment. Nature of projects and their environments are associated with uncertain conditions. In this paper, a new project cash flow assessment method based on project scheduling is proposed t...

Improvement in ultrasound technology, including transvaginalsonography and higher frequency probes, has led to a better understanding of early pregnancy development. The first trimester ultrasound have been identified that can be used to reassure women that their pregnancy is progressing normally or abnormal them that their pregnancy will fail. The practicing radiologist and obstetrician must b...

quantitative assessment is the most important means to identify hazard potential and manage risk for an industrial process. the implement of quantitative assessment in the early stage will help to develop inherently safer process, eliminating the hazard and reduce the possibility of accidental chain events and the magnitude of consequences. in this paper, after reviewing the presently available...

early warning systems are key components of strategies to reduce risk. this research, by adopting a systematic approach in the management of the risk of desertification and by including previously developed models and systems, offers an integrated efficient structure in terms of early warning for the risk of desertification as a pilot system for semi-arid areas of west golestan province in iran...