Objectives: The present study was carried out to evaluate the antiinflammatory effect of extracts of leaves of Vitex trifolia Linn. (Verbaneaceae). Methods: The anti inflammatory activity of plant extracts at different dose intervals was evaluated by using two models Carrageenan induced rat paw edema and Xylene induced ear edema in Mice. Acute inflammation in rats was induced by injecting Carra...

Background & Aim: The treatment of Parasagittal Meningioma (PSM) is always a challenge, especially when the tumor has already invaded the critical structures like venous sinuses. This study aims at evaluating the outcomes of Gamma Knife Radiosurgery (GKRS) in patients with PSM. Methods and Materials/Patients: In this descriptive retrospective study, we reviewed the medical records of 61 patien...

FORMATION of noncardiogenic pulmonary edema has been observed after a variety of inciting events, including upper airway obstruction (negative pressure pulmonary edema [NPPE]), acute lung injury, anaphylaxis, fluid maldistribution, and severe central nervous system trauma (neurogenic pulmonary edema). Both the diagnosis of pulmonary edema and an understanding of its underlying pathophysiology h...

For the first time, we have implemented photoacoustic tomography (PAT) to image the water content of an edema in vivo. We produced and imaged a cold-induced cerebral edema transcranially, then obtained blood vessel and water accumulation images at 610 and 975 nm, respectively. We tracked the changes at 12, 24, and 36 h after the cold injury. The blood volume decreased after the cold injury, and...

The effectiveness of stereotactic gamma-radiosurgery for treating acoustic neurinoma was evaluated by measuring the volumes of the tumor, non-enhanced tumor, and cerebellar edema in 13 patients with acoustic neurinoma who were followed up for 9 to 15 months (median 12.7 mos) after treatment. The tumor volume and non-enhanced volume tended to reach a maximum after 6 months, and cerebellar edema ...

During single pass indicator studies across the lungs [(14)C]urea remains in the vascular compartment, but its molecular size and solubility suggest it might escape abnormally permeable vessels. To test the hypothesis that [(14)C]urea might be used to distinguish pulmonary edema due to acutely increased intravascular pressure from that due to vascular damage by alloxan, we studied [(51)Cr]eryth...

Pathological conditions in the central nervous system, including stroke and trauma, are often exacerbated by cerebral edema. We recently identified a nonselective cation channel, the NCCa-ATP channel, in ischemic astrocytes that is regulated by sulfonylurea receptor 1 (SUR1), is opened by depletion of ATP and, when opened, causes cytotoxic edema. Here, we evaluated involvement of this channel i...

This paper will discuss the recent finding that the normal interstitial fluid pressure is negative rather than positive and will present a method for recording dynamic changes in interstitial fluid pressure. Especially important is the shape of the pressure-volume curve of the interstitial spaces. So long as the interstitial fluid pressure is negative, the interstitial fluid volume remains almo...