We report an 11-year-old girl with euthyroid Graves' disease. She was referred to our clinic because of left exophthalmos without other symptoms suggestive of hyperthyroidism. Her serum concentration of free thyroxine (FT4) and free triiodothyronine (FT3) were normal, but thyroid-stimulating hormone (TSH) was below normal and impaired TSH response to TSH releasing hormone (TRH) was found. Altho...

33 patients with active, moderate-severe Graves' ophthalmopathy (GO) received 4.5 g methylprednisolone for 12 weeks and were divided by efficacy into two groups (responsive and unresponsive). All patients and 10 controls underwent orbital MRI examination at baseline. No significant difference was seen in baseline clinical characteristics between the two GO groups. The values of exophthalmos wer...

A 61-year-old male presented with a rapidly progressive exophthalmos from small cell lung cancer metastatic to the right orbit. His vision in that eye was 20/200, and his intraocular pressure was 36 mmHg. The orbital metastasis responded dramatically to chemotherapy. One week after starting the chemotherapy the patient did not have exophthalmos, his vision was 20/20, and three weeks later the i...

was said to have commenced after an attack of fever, eighteen months previous to his admision into hospital. He was at first under Dr. Fayrer's care, but, on his leaving India, in February, became a patient of mine. He has been a very temperate and hard-working man. During the first four months of his illness he could see to such an extent as to be able to find his way about, and to distinguish...

Thyroid ophthalmopathy, or Graves’ ophthalmopathy, is the most common cause of exophthalmos in adults. Graves first described thyroid disease with associated ophthalmopathy in 1835. To date, the pathogenesis of thyroid ophthalmopathy remains speculative, as reflected by the numerous names by which it is described such as dysthyroid ophthalmopathy or thyroid eye disease, thyroid orbitopathy, eut...

Radiographic findings may be very helpful in deciding adequate management. A cystic image with fluid contents and an attenuation coefficient similar to water containing calcifications (occurring in up to 15% of cases) may suggest an adrenal cyst. Rozenblit et al. classified nonfunctioning cystic adrenal masses into four types based on radiographic criteria. Uncomplicated cysts are homogeneous c...