A 20-year-old woman suffered gradual progression of right pulsatile exophthalmos and slight headache. Computed tomography (CT) demonstrated outward and downward displacement of the right globe and an arachnoid cyst in the right middle cranial fossa associated with thinned and anterior protrusion of a bony orbit. Microscopic cystocisternotomy was performed and the cerebrospinal fluid (CSF) insid...

Exophthalmos is typically associated with Graves' ophthalmopathy. Although originally described by Harvey Cushing, exophthalmos is an underappreciated sign of Cushing's syndrome. We present a case of a 38-year-old female who presented with severe bilateral proptosis and was subsequently diagnosed with Cushings disease. We discuss the possible mechanisms causing exophthalmos in patients with eit...

(a) Hyperthyroid or Thyrotoxic Exophthalmos.-This accompanies Graves's disease and is, therefore, much more frequently seen in females than in males. In the majority of cases the exophthalmos is quite unobtrusive or there is merely an appearance of exophthalmos due to retraction of the upper lid. It is associated with a decreased frequency of blinking and a fixed stare. The majority of authors ...

A 58-year-old woman suddenly developed right exophthalmos. A CT scan of her orbit revealed an increase in volume and density of extraocular muscles and intraorbital soft tissues that resembled exophthalmos in Graves' disease. The exophthalmos gradually improved without treatment. Two months later she developed mononeuritis multiplex in her limbs, and then showed a sudden onset of swelling of he...

We report a patient with malignant exophthalmos associated with multiple myeloma which showed no evidence of direct orbital involvement of plasma cells. This exophthalmos had similarities with Graves' ophthalmopathy, but the patient had no detectable autoimmune thyroid diseases. Plasmapheresis was effective not only for the treatment of heart and renal failure due to the myeloma kidney but also...

exophthalmos, myxedema, and acropachy are collectively named exophthalmos myxedema acropachy (ema) syn-drome, which is a rare syndrome associated with hypertcardiotrophia. among patients with hyperthyreosis, ema has an incidence less than 1%. here, we reported a case of ema and explored its diagnosis and treatment.

Goldfish (Carassius auratus, var. japonicus, subvar. bicaudatus) respond to the administration of thyrotrophic hormone with exophthalmos. Eye protrusion increases with simultaneous injections of corticotrophin. Retrobulbar injections of normal saline, human serum or pituitary hormones produce a transient exophthalmos, which is much more persistent when thyrotrophin is injected. Previous treatme...

UNDER the heading "endocrine exophthalmos" we may consider on the one hand thyrotoxic exophthalmos and on the other the condition which has been designated exophthalmic ophthalmoplegia, malignant exophthalmos, thyrotropic exophthalmos, and also as a hyperophthalmopathic form of Graves's disease (Means, 1945). As Wybar (1956) has emphasized, the separation of endocrine exophthalmos into the thyr...