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تعداد نتایج: 549468 فیلتر نتایج به سال:
Glucocorticoid hormones are critical to respond and adapt to stress. Genetic variations in the glucocorticoid receptor (GR) gene alter hypothalamic-pituitary-adrenal (HPA) axis activity and associate with hypertension and susceptibility to metabolic disease. Here we test the hypothesis that reduced GR density alters blood pressure and glucose and lipid homeostasis and limits adaption to obesoge...
Background and purpose: Obstetricians and neonatologists have a major challenge in determining the viability of preterm newborns that has an important role in choosing the mode of delivery and evaluation of post-natal care. This study, evaluated the viability of preterm infants born in Ghaem Hospital in Mashhad Materials and methods: This descriptive–analytical study was performed between 2009...
The present study was conducted to investigate the effects of dietary lysine (Lys) and sex on growing quail performance and immunity parameters. The six dietary Lys: 10, 11.5, 13.0 (NRC 1994 recommendation), 14.5, 16.0 and 17.5 gr/kg were provided. The other essential amino acids except lysine were provided to meet or exceed NRC 1994 recommendation for growing quail. This experiment was carried...
Epidemiological evidence suggests that low birth weight is associated with an increased risk of cardiovascular, metabolic and neuroendocrine disorders in adult life. Glucocorticoid administration during pregnancy reduces offspring birth weight and alters the maturation of the lung and other organs. We hypothesised that prenatal exposure to excess glucocorticoids or stress might represent a mech...
BACKGROUND The laparoscopic sleeve gastrectomy (LSG) is a successful surgical procedure for morbid obesity. However, post surgery weight regain is usual, thus applying the glycemic index could promote good weight control. OBJECTIVE To compare the glycemic index (GI) and glycemic response (GR) obtained of instant mashed potatoes in individuals subjected to LSG versus control subjects. METHOD...
BACKGROUND Golden Rice (GR) has been genetically engineered to be rich in β-carotene for use as a source of vitamin A. OBJECTIVE The objective was to compare the vitamin A value of β-carotene in GR and in spinach with that of pure β-carotene in oil when consumed by children. DESIGN Children (n = 68; age 6-8 y) were randomly assigned to consume GR or spinach (both grown in a nutrient solutio...
Methylprednisolone (MP), a glucocorticoid, is the only effective therapeutic agent used in the clinical treatment of acute spinal cord injury (SCI). MP given within 8 hr after SCI significantly improves neurological function. Although the glucocorticoid receptor (GR) is suggested to mediate MP actions, limited knowledge is available on its expression and possible function after SCI. Presently, ...
Proposal GR/M70186 followed fairly close on the heels of a related funding application (GR/M20402). GR/M20402 sought modest equipment/consumables funding to allow a number of modifications to an existing ion imaging apparatus, plus a contribution towards the salary of a technician and a project studentship. In the event, all bar the studentship was awarded. This decision was seemingly based on ...
Glucocorticoid receptor α (GR) binds to the promoter regions of target genes as a homodimer and activates its transcriptional process. Though the homodimerization is thought to be the initial and essential process, the dissociation constant for homodimerization of GR remains controversial. To quantify homodimerization of (enhanced green fluorescence protein) EGFP-(glucocorticoid receptor) GR, t...
The aim of present study was to estimate genetic and phenotypic trends for body weight traits at some ages in Lori-Bakhtiari lambs. In this study a total of 7721 records on birth weight, 6462 records of one month weight, 7275 records of weaning weight 5745 records of 6 month weight, 3326 records of 9 month weight and 3088 records of 12 month weight of Lori-Bakhtiari sheep was used to reveal the...
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