Piroxicam belongs to BCS class II and has low solubility. Self-nanoemulsifying drug delivery systems (SNEDDS) are considered a potential approach for increasing the solubility release of piroxicam. This study aimed select components component ratios piroxicam SNEDDS using fractional factorial design 26-2 (FFD). The variables used in DFT development type concentration oil (triacetin oleic acid),...

This paper focuses on the calibration of heat source parameters to reproduce temperatures and distortions in welded joints. Specifically, proposed methodology, which combines Finite Element Method Design Experiments, is applied calibrate a T-joint dissimilar titanium laser welding process. The thermal problem addressed using 3D transient model with Conical Gaussian flux, mechanical tackled elas...

We present some optimal criteria to evaluate model-robustness of non-regular two-level fractional factorial designs. Our method is based on minimizing the sum of squares of all the off-diagonal elements in the information matrix, and considering expectation under appropriate distribution functions for unknown contamination of the interaction effects. By considering uniform distributions on symm...

Inferences we make about underlying cognitive processes can be jeopardized in two ways due to problematic forms of aggregation. First, averaging across individuals is typically considered a very useful tool for removing random variability. The threat is that averaging across subjects leads to averaging across different cognitive strategies, thus harming our inferences. The second threat comes f...

Mixed-level fractional factorial designs are commonly used in industries but its aliasing relations have not been studied in full rigor. These designs take the form of a product array. Aliasing patterns of mixed level factorial designs are discussed here.

Box and Hunter (1961) made an important observation that any fractional factorial design of resolutionR has the property that when projected onto anyR 1 factors it becomes a full factorial design. This has a signi cant implication for statistical analysis. We observe that the Plackett-Burman and related designs have a hidden projection property with an analogous implication for the analysis. Be...