INTRODUCTION Patients with mild to moderate obstructive sleep apnoea (OSA) commonly suffer excessive daytime sleepiness. Continuous positive airway pressure (CPAP) has limited effectiveness in reducing sleepiness in milder OSA. Modafinil is a wake-promoting drug licensed to treat residual sleepiness in CPAP-treated OSA. We hypothesised that modafinil may effectively treat sleepiness in untreate...

OBJECTIVE To compare the effects of 800 mg of valerian with a placebo on sleep quality and symptom severity in people with restless legs syndrome (RLS). METHODS A prospective, triple-blinded, randomized, placebo-controlled, parallel design was used to compare the efficacy of valerian with placebo on sleep quality and symptom severity in patients with RLS. Thirty-seven participants were random...

traffic fatalities are a major cause of morbidity and mortality in iran. occupational sleep medicine field needs more cost-effective and applicable tests for screening purposes. this study reports on a pilot screening study for drowsy drivers in an urban iranian sample of commercial drivers. the maintenance of wakefulness test (mwt) measures the ability to remain awake objectively. sleep latenc...

Abstract Introduction Obstructive sleep apnea (OSA) is an increasingly prevalent sleep-related breathing disorder linked to cognitive dysfunction and daytime sleepiness. Positive airway pressure (PAP) therapy, the first-line treatment for OSA, may improve function sleepiness, but responses vary. Hypoglossal nerve stimulation (HGNS) a novel effective PAP alternative, its effect on mitigating dec...

OBJECTIVE This study examined associations among adolescent sleepiness, sleep duration, variability in sleep duration, and psychological functioning (symptoms of anxiety, depression, externalizing behaviors, and perceived health). METHODS This was a cross-sectional analysis of data from a community-based cohort study of sleep and health. Participants were 247 adolescents (48.6% female, 54.3% ...

METHOD Retrospective review of medical records from patients with multiple sclerosis to collect data on severity of fatigue, disability, daytime sleepiness, and depression. From 912 medical records reviewed, 122 reported daytime sleepiness: 67% had relapsing remitting, 12% had primary progressive, and 21% had secondary progressive. RESULTS In 95% of the patients with relapsing remitting who c...

OBSTRUCTIVE SLEEP APNEA IS BELIEVED TO CAUSE SLEEPINESS IN 3% OF ADULTS,1 BUT THE MECHANISM BY WHICH SLEEPINESS AND OTHER COGNITIVE CHANGES ARE PRODUCED IS NOT COMPLETELY UNDERSTOOD.2 Although hypoxemia may play some role,3 much attention has focused on the role of arousals, which typically occur at the termination of each apnea, hypopnea, or transient period of increased respiratory effort.4,5...