phototherapy is a conventional method of lowering serum bilirubin in newborn jaundice. we evaluated the short distance in relation to conventional long distance phototherapy between the light-source and the skin surface. healthy jaundiced neonates undergoing phototherapy were randomized into two groups. the distance between the light-source and the newborn's skin was 20 and 40 centimeters (g20;...

Background: Preeclampsia has high prevalence and important complication. The relationship between Glucose- 6-Phosphate Dehydrogenas (G6PD) and preeclampsia are expressed previously but their relationships are controversial yet. Some studies confirm this possibility and some others dismiss it. So we decided to examine the relationship between G6PD activity and preeclampsia although it is not den...

Glucose-6-phosphate dehydrogenase (G6PD) deficient subjects are vulnerable to oxidative stress. Quercetin, a flavonoids, has been employed as a potent oxygen-free radical scavenger in order to assess the protective effects of quercetin against H2O2-induced oxidative damage in G6PD-deficient and normal human erythrocytes. Erythrocytes of G6PD-deficient (n = 10) and normal (n = 10) subjects were ...

Deficiency in glucose-6-phosphate dehydrogenase (G6PD), an X-linked recessive red cell enzymopathy, is endemic in Southern Chinese. Universal screening of newborn is done in Hong Kong, Taiwan and Singapore, among other places. In Hong Kong, 4.8% of males are affected and seven common G6PD alleles account for over 99% of all defects. Male hemizygotes suffer from severe deficiency, while female h...

BACKGROUND Previously published data have demonstrated that sickle red blood cells produce twice as much reactive oxygen species (ROS) suggesting that co-inheritance of sickle cell disease (SCD) and glucose 6-phosphate dehydrogenase (G6PD) enzymopathy could lead to more severe anaemia during sickling crises. Elevated foetal haemoglobin (Hb F) levels have been shown to have positive modulatory e...

Background: Glucose-6-phosphate dehydrogenase deficiency is an enzymopathy characterized by insufficient production of reduced glutathione (GSH), a molecule known for its antioxidant role. This lack GSH leads to deficit in the elimination peroxide ions from red blood cells, causing thereby hemolytic accidents, which can be fatal if not properly managed. In neonates, clinical picture most often ...

Objective Glucose 6-phosphate dehydrogenase (G6PD) deficiency increases the risk of neonatal hyperbilirubinemia. The aim this study is to evaluate factors associated with hyperbilirubinemia in infants from western part Guangdong Province, and assess contribution G6PD jaundice. Methods term People's Hospital Yangjiang June 2018 July 2022 were recruited for retrospective analysis. All underwent q...

glucose-6-phosphate dehydrogenase (g6pd) deficient subjects are vulnerable to oxidative stress. quercetin, a flavonoids, has been employed as a potent oxygen-free radical scavenger in order to assess the protective effects of quercetin against h2o2-induced oxidative damage in g6pd-deficient and normal human erythrocytes. erythrocytes of g6pd-deficient (n = 10) and normal (n = 10) subjects were ...

Glucose-6-phosphate dehydrogenase (G6PD) deficiency and hemoglobin E (HbE, β26 Glu-Lys) are two common red cell disorders in Southeast Asia. G6PD deficiency produces hemolytic anemia, which can be triggered by certain drugs or infections. HbE is asymptomatic or is manifested as microcytic, minimally hemolytic anemia. The association between G6PD deficiency and HbE is little understood. This stu...