698 September 2013 D espite the introduction of B-mode ultrasound into regional anesthesia, no evidence suggests any reduction in the incidence of unintentional intraneural injection.1 B-Mode ultrasound has several limitations: structures with similar scattering characteristics are difficult to differentiate; image quality is inconsistent among patients and deteriorates with age; and block need...

This work describes a study of vibration characteristics of thin circular plates with elastic edge support and resting on partial Winkler-type elastic foundation. The foundation is described by the Winkler model, which is called as single parameter foundation. The exact analytical method is used to derive the frequency equation of the circular plate with elastic edge support-conditions and rest...

Groove is a key structure of high-performance integral cutting tools. It has to be manufactured by 5-axis grinding machine due its complex spatial geometry and hard materials. The crucial manufacturing parameters (CMP) are wheel positions geometries. However, it challenging problem solve the CMP for designed groove. traditional trial-and-error or analytical methods have defects such as time-con...

WOPR-domain proteins are found throughout the fungal kingdom where they function as master regulators of cell morphology and pathogenesis. Genetic and biochemical experiments previously demonstrated that these proteins bind to specific DNA sequences and thereby regulate transcription. However, their primary sequence showed no relationship to any known DNA-binding domain, and the basis for their...

We present here for the first time the crystal structure of an AT-hook domain. We show the structure of an AT-hook of the ubiquitous nuclear protein HMGA1, combined with the oligonucleotide d(CGAATTAATTCG)(2), which has two potential AATT interacting groups. Interaction with only one of them is found. The structure presents analogies and significant differences with previous NMR studies: the AT...

Atomic force microscopy was used to measure the thickness of air-dried, collapsed murein sacculi from Escherichia coli K-12 and Pseudomonas aeruginosa PAO1. Air-dried sacculi from E. coli had a thickness of 3.0 nm, whereas those from P. aeruginosa were 1.5 nm thick. When rehydrated, the sacculi of both bacteria swelled to double their anhydrous thickness. Computer simulation of a section of a m...

Thin-walled structures like crash boxes may be used as energy absorption members in automotive chassis. There have been many studies addressing the behaviors of energy absorption members on frontal crash. These researches have attempted to predict the energy absorption and maximum impact load in shell structures. The energy absorption and maximum impact load depend on many parameters including ...

Diffuse interreflections cause effects that make current theories of shape from shading unsatisfactory. We show that distant radiating surfaces produce radiosity effects at low spatial frequencies. This means that, if a shading pattern has a small region of support, unseen surfaces in the environment can only produce effects that vary slowly over the support region. It is therefore relatively e...

A flexible structure is applied to improve the lubrication performance of a misaligned journal bearing. The bearing representative sliding bearing, and there damage due metal-to-metal contact as result misalignment. Since misalignment an unavoidable phenomenon, with was proposed way it. characteristics were evaluated numerically under steady-state condition. EHL (elastohydrodynamic lubrication)...