In this paper a four-ball-best-ball (4BBB) model for pairs of golf players is set up. The 4BBB match-play scoring system is seen to satisfy a basic requirement of fairness. It is shown that it is not strictly possible to rate individual players as 4BBB players. However, a (reasonably broad) class of individual players is identified such that it is possible to rate them individually as 4BBB play...

An increasing number of reports indicate that endogenously produced inhibitors of nitric oxide synthase, particularly asymmetric dimethylarginine (ADMA), regulate nitric oxide generation in disease states. This article describes the biology of ADMA and the implications for cardiovascular physiology and pathophysiology.

Three new pavine N-oxide alkaloids, (-)-isocaryachine-N-oxide B, (+)-caryachine-N-oxide, (-)-caryachine-N-oxide, and a new isoquinoline alkaloid, 6,7-methylenedioxy-N-methylisoquinoline together with 11 known alkaloids were isolated and characterized from the stem bark of Cryptocarya chinensis. The structures of the isolated compounds were determined by spectral methods. The stereochemistry of ...

ADMA, a product of protein degradation, is an endogenous nitric oxide synthase inhibitor that has been shown to be increased in mouse models of allergic airway inflammation and to be associated with airways hyperresponsiveness in these animals [2]. ADMA has also been reported to be increased in sputum samples [2] and exhaled breath condensates [3] from paediatric patients with asthma. Increased...

Asymmetrical dimethylarginine (ADMA), an endogenous inhibitor of nitric oxide synthase (NOS), impairs the beneficial effect of NO. The predictive value of ADMA for all-cause mortality remains controversial, though it is important in the development of cardiovascular disease (CVD) and progression to dialysis in renal disease. This systematic review and meta-analysis was conducted to investigate ...

background: cyclosporine a (csa) is an immunosuppressant with therapeutic indications in various immunological diseases; however, its use is associated with chronic nephropathy. oxidative stress has a crucial role in csa-induced nephrotoxicity. the present study evaluates the protective effect of edaravone on csa-induced chronic nephropathy and investigates its antioxidant and nitric oxide modu...

Under experimental conditions, the effect of plant proanthocyanidin – yantacin isolated from a camel thorn (Alhagi pseudalhagi) Yantacin, when administered orally at dose 100 mg / kg, on possible changes in early stages liver fibrosis that occurred against background chronic heliotrine hepatitis was studied. The studies were conducted male rats with body weight ±10 g. general and biochemical pa...