Background. Persistent infection with high-risk human papillomavirus (HR-HPV) has been demonstrated to be the necessary causal factor for developing cervical cancer. To know the most prevalent HR-HPV in different geographical areas is important to design diagnostic tests and implementation of vaccines. Objectives. The goal of this study is to evaluate the prevalence of HR-HPV in a total of 1001...

conclusions this results the same as many similar studies demonstrated that common hcv genotypes in iranian patients were 1a, 3a and 1b, respectively. patients with 1a and 1b genotypes have lower responses to interferon treatment, and it is reasonable to perform early screening to diagnose and determine hcv genotype for effective treatment and diagnose high-risk cases. results in overall, 509 p...

abstract   background: due to the high incidence of breast cancer and the effect of its early diagnosis on decreasing morbidity and mortality, we used the gail model to study breast cancer risk in iranian women.   methods: this study was done in a simple randomized way. participants were 2000 iranian women older than 35 years old. the questionnaire consisted of demographic data such as age, rac...

background: long distance truck drivers (ldtds) and their sexual health risk behaviors have been associated with greater prevalence of sexually transmitted infections (stis), hiv and hepatitis virus transmission. however, there is no information about iranian ldtds' high-risk behaviors. the aim of this investigation was to estimate the prevalence of high-risk behaviors in iranian ldtds. methods...

conclusions the results of this study suggested that parental monitoring and affiliation with deviant peers largely explained sexual risk taking among adolescents. therefore, prevention efforts aimed at reducing risky sex should compose of these factors. in fact, the results suggested that earlier prevention efforts may be warranted. results according to the results, about one-fifth of subjects...

Estrogen has been proposed to trigger breast cancer development via an initiating mechanism involving its metabolite, catechol estrogen (CE). To examine this hypothesis, we conducted a multigenic case-control study to determine whether polymorphisms of the genes responsible for CE formation via estrogen biosynthesis (CYP17) and hydroxylation (CYP1A1) and CE inactivation (COMT) are associated wi...

OBJECTIVES High-risk human papillomaviruses (hrHPVs) are highly prevalent worldwide, and HPV genotypes differ between geographical regions; however, sexually transmitted HPV may lead to cervical carcinogenesis. The objective of this cross-sectional study was to estimate the prevalence characteristics of cervical HPV genotypes in Taizhou, Southeast China. SETTING AND PARTICIPANTS A population-...

Objective(s): To investigate the association of single nucleotide polymorphisms (SNPs) in the peroxisome proliferator-activated receptors gamma (PPARG) with essential hypertension (EH) and additional role of gene– high-density lipoprotein cholesterol (HDL) interaction. Materials and Methods:A total of 1640 patients with EH (806 males, 834 females), with a mean age of 52.5±12.6 years, were selec...

In the current study, we examined the association between polymorphisms in the O(6)-methylguanine-DNA methyltransferase gene (MGMT) and the risk for cervical carcinoma. We prospectively selected 1012 patients, including 539 with carcinoma and 473 with cervical intra-epithelial neoplasia and 800 healthy women from five hospitals in Zhejiang Province, China. Three single-nucleotide polymorphisms ...