Hydroxyapatite (HA) is a precursor of bone and has been studied as a biomaterial. We attempted HA to apply to protein delivery systems. In this study, the association and dissociation properties of two types of bioactive proteins, cytochrom c and insulin, to HA were investigated. Cytochrom c was less associated with HA than insulin, which was easily released from it. However, the release of ins...

Batch experiments were conducted to evaluate the ability of hydroxyapatte (HA) to reduce the solubility of metals, including the primary contaminants of concern, Ni and U, from contaminated sediments located on the Department of Energy's Savannah River Site, near Aiken, SC. Hydroxyapatitie was added to the sediments at application rates of 0, 5, 15.8, and 50 g kg-1. After equilibrating in eithe...

     In this study, hydroxyapatite (HA) nanocrystals have been synthesized via chemical precipitation technique. Diammonium hydrogen phosphate and calcium nitrate 4-hydrate were used as starting materials and sodium hydroxide solution was used as the agent for pH adjustment. The powder sample was evaluated by techniques such as scanning electron microscope, transmission electron microscope, Fou...

Hydroxyapatite (HA) has been widely investigated as scaffolding material for bone tissue engineering, mainly for its excellent biocompatibility. Presently, there is an increasing interest in the composites of hydroxyapatite with bioactive glasses, with the aim to obtain systems with improved bioactivity or mechanical properties. Moreover, modifying the ratio between bioactive glass and hydroxya...

INTRODUCTION Microorganisms are essential in the development of periradicular diseases and are the major causative factors associated with endodontic treatment failures. Microbial biofilms are communities of bacteria that attach to surfaces and form heterogeneous three-dimensional structures. The purpose of this study was to develop a biofilm model that closely mimicked in vivo biofilm and to d...

Article history: Received 17 July 2015 Revised 18 December 2015 Accepted in revised form 19 December 2015 Available online 21 December 2015 The main challenges of biological implants are suitable strength, adhesion, biocompatibility and corrosion resistance. This paper discusses fabrication, characterization and electrochemical investigation of anodized Ti6Al4V without and with a hydroxyapatite...

Bovine serum albumin (BSA) may have an inhibitory or promoter effect on hydroxyapatite (HA) nucleation when apatite is precipitated in a medium containing the protein. In this study we evaluated the influence of BSA on the precipitation of calcium phosphate phases (CP) from simulated body fluid (SBF) when the protein was previously bounded to HA surface. The kinetics of BSA immobilization onto ...

Phase variation of Streptococcus gordonii between high (Spp+) and low (Spp-) levels of glucosyltransferase (GTF) activity resulted in the greater adhesion of Spp- strains to saliva-coated hydroxyapatite (S-HA) in a washed-cell adhesion test. Specific GTF mutants did not show this response. Although washed Spp+ cells produced 5-fold or more glucan from sucrose than Spp- cells did under the condi...

More than twenty years ago, hydroxyapatite (HA), calcium phosphate ceramics, was introduced as a coating for cementless hip prostheses. The choice of this ceramic is due to its composition being similar to organic apatite bone crystals. This ceramic is biocompatible, bioactive, and osteoconductive. These qualities facilitate the primary stability and osseointegration of implants. Our surgical e...