نتایج جستجو برای: inhibitory effective concentration
تعداد نتایج: 1128243 فیلتر نتایج به سال:
The aim of this study was to evaluate the antibacterial activity of the water extracts of three species of Salvia (S. perspolitana, S. palaestina, S. bracteata) on Staphylococcus aureus, Escherichia coli and Pseudomonas aeroginosa. The antibacterial activity of water extracts of the studied species on the bacterial strains was examined using well diffusion method and minimum inhibitory concentr...
growth inhibition of aspergillus fumigatus,aspergillus flavus and fusarum solani exposed to the essential oils including thyme, agastache and satureja were studied. disc diffusion method was used to evaluate the fungal growth inhibitory effects of the essential oils. minimal inhibitory concentration (mic) and minimal fungicidal concentration (mfc) of the oils were determined and compared with e...
A series of 2-N-alkyl-3-aryl-3-alkoxyisoindolinones has been synthesised and evaluated as inhibitors of the MDM2-p53 interaction. The most potent compound, 3-(4-chlorophenyl)-3-(4-hydroxy-3,5-dimethoxybenzyloxy)-2-propyl-2,3-dihydroisoindol-1-one (NU8231), exhibited an IC50 of 5.3 +/- 0.9 microM in an ELISA assay, and induced p53-dependent gene transcription in a dose-dependent manner, in the S...
Based on a known pharmacophore model for 5-HT₆ receptor antagonists, a series of novel extended derivatives of the N-arylsulfonyindole scaffold were designed and identified as a new class of 5-HT₆ receptor modulators. Eight of the compounds exhibited moderate to high binding affinities and displayed antagonist profile in 5-HT₆ receptor functional assays. Compounds 2-(4-(2-methoxyphenyl)piperazi...
Growth inhibition of Aspergillus fumigatus,Aspergillus flavus and Fusarum solani exposed to the essential oils including Thyme, Agastache and Satureja were studied. Disc Diffusion Method was used to evaluate the fungal growth inhibitory effects of the essential oils. Minimal inhibitory concentration (MIC) and minimal fungicidal concentration (MFC) of the oils were determined and compared with ...
198 lactic acid bacteria (lab) were isolated from iranian milk samples. almost all isolatedlab showed inhibitory activity towards e. coli and s. aureus as gram negative and grampositive indicators, respectively. no role was observed for hydrogen peroxide in the activity ofall isolated strains while organic acids proved a prominent role in all detected inhibitoryactivities. within isolated lab, ...
oral ph sensitive drug delivery systems are of utmost importance as these systems deliver the drug at specific part of the gastrointestine (gi) as per the ph of gi, resulting in improved patient therapeutic efficacy and compliance. the ph range of fluids in various segments of the gi tract may provide environmental stimuli for drug release. the aim of this study was to design buoyant beads cont...
Although, arsenic trioxide has been the subject of toxicological research, in vitro cytotoxicity and genotoxicity studies using relevant cell models and uniform methodology are not well elucidated. Hence, the aim of the present study was to evaluate the cytotoxicity and genotoxicity induced by arsenic trioxide in human keratinocytes (HaCaT) using the MTT [3-(4, 5-dimethylthiazol-2-yl)2,5-diphen...
An effective method was elaborated for extracting the active substances from commercially available Garden thyme and carob seeds. The antibacterial activity of dilutions of thyme and carob extracts and their combinations were studied by taking the minimum inhibitory concentrations (MIC) with agar well diffusion technique. The most effective concentrations of the two herb extracts were used for ...
conclusions p. aeruginosa and s. marcescens can be good candidates for the detoxification of cr (vi) in soltan abad river. results the results indicated that pseudomonas aeruginosa and serratia marcescens were the most resistant bacteria with mics of 200 and 150 mg/l, respectively. both bacteria completely reduced 25 and 50 mg/l of cr (vi) in 36 hours and 48 hours, respectively. the growth rate...
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