Drug-drug interaction (DDI) is one of the most important problems in the treatment of patients suffering from different chronic intractable diseases. The war-injured veterans are one of the groups that are prone to chronic refractory diseases. This investigation was conducted on war-injured veterans treated in a multi-disciplinary clinic in Tehran. Using Poisson model, a total of 150 patients w...

Concomitant use of several drugs by ICU( Intensive Care Unit) patients is often unavoidable. In these patients, pharmacokinetic drug interactions are very likely. The current study was designed to evaluate these interactions in patients hospitalized in an ICU of a teaching hospital in Tehran, Iran. A questionnaire was designed and used to collect study data. The study was done in the ICU of a t...

Concomitant use of several drugs by ICU( Intensive Care Unit) patients is often unavoidable. In these patients, pharmacokinetic drug interactions are very likely. The current study was designed to evaluate these interactions in patients hospitalized in an ICU of a teaching hospital in Tehran, Iran. A questionnaire was designed and used to collect study data. The study was done in the ICU of a t...

streptokinase is a potent fibrinolytic agent which is widely used in treatment of deep vein thrombosis (dvt), pulmonary embolism (pe) and acute myocardial infarction (mi). major limitation of this enzyme is its short biological half-life in the blood stream. our previous report showed that complexing streptokinase with chitosan could be a solution to overcome this limitation. the aim of this re...

in this paper, we discuss the ways that communication accommodation theory (cat) can be a useful framework for understanding and diagnosing interactional issues in interpersonal and intergroup conflict situations. we argue that the theory’s construct of attuning strategies provides a multidimensional view of mutual adjustment, leading to insights relevant to successful versus unsuccessful confl...

background : drug-drug interactions (ddis) are adverse reactions caused by a combination of drugs; they are often predictable and therefore avoidable or manageable. the objective of this study was to evaluate the nature, type and prevalence of potential ddis in prescriptions dispensed in university-based community pharmacies in tehran, iran. methods: from july 2012 to february 2014, sample of 1...

objectives: genetic polymorphism interactions are among the important factors in affliction with complex diseases like alzheimer’s disease. the important goal of genetic association studies is to identify a combination of polymorphisms and measure their importance in increasing the risk of occurrence of such diseases. in this study, feature selection approach of logic regression was used to ide...

human serum albumin (hsa) is the most abundant protein constituent of blood plasma. this protein consists of a single polypeptide chain of 585 amino acid residues, which has many important physiological functions. hsa can bind and carry many drugs, including anticoagulants, tranquilizers, and general anesthetics. some technique such as: fluorescence spectroscopy, three-dimensional fluorescence ...

conclusions bacillus thuringiensis is very sensitive to the interaction of p. fluorescens, however is capable to survive in soil due to its capacity of sporulate. some of the cells in the form of spores germinated and folded slightly and remained in a constant cycle of sporulation and germination. this confirms that b. thuringiensis ips82 can germinate, grow and sporulate in soil. results the a...

in this paper, we discuss the ways that communication accommodation theory (cat) can be a useful framework for understanding and diagnosing interactional issues in interpersonal and intergroup conflict situations. we argue that the theory’s construct of attuning strategies provides a multidimensional view of mutual adjustment, leading to insights relevant to successful versus unsuccessful confl...