Pituitary gland is an uncommon site of metastasis for malignancies. However, breast cancer is the most common primary metastasizing to hypophysis in women. It may cause hormonal problems in different patterns due to mass affect and invasion to pituitary gland. We present a 53-year-old woman with HER-2 positive breast cancer presenting with intermittent symptoms of diabetes insipidus and rapidly...

BACKGROUND Various types of preoperative chemoradiotherapy (CRT) have been established for rectal cancer; thus, Physicians will need to refine the selection of appropriate preoperative CRT for different patients since there are various treatment regimens. Oral tegafur-uracil (UFT) plus leucovorin (LV) is commonly used to treat rectal cancer in Japan. Oral chemotherapy offers patients many poten...

Wolbachia pipientis is an obligate intracellular bacterium within the family Anaplasmataceae that infects many terrestrial arthropods and arthropod-transmitted nematodes (filariae). Several filarial species are major human pathogens, and antibiotics with activity against Wolbachia offer a promising new therapeutic approach, since the adult worms are relatively refractory to conventional anthelm...

the purpose of this study was to determine the relationship between blood buffer capacity and aerobic power (vo2max) with ability to perform high intensity intermittent activities in young football players. methods: 27 male football players (age 17.66 ±0.49 years) selected as subjects. blood samples were collected before and after the yoyo intermittent test. then, after 48 hours, the bruce trea...

A 64-year-old man was admitted to West Virginia University Hospital in July 1974 for evaluation of a left inguinal mass of three months' duration and a more recently enlarged right axillary mass. Biopsy at both sites showed diffuse poorly differentiated lymphocytic lymphoma. IHe was subjectively well and physical examination was otherwise normal. Laboratory data showed a haemoglobin of 15-0 gra...

Calorie restriction (CR) extends lifespan and has been shown to reduce age-related diseases including cancer, diabetes, and cardiovascular and neurodegenerative diseases in experimental models. Recent translational studies have tested the potential of CR or CR mimetics as adjuvant therapies to enhance the efficacy of chemotherapy, radiation therapy, and novel immunotherapies. Chronic CR is chal...

introduction mild intermittent asthma is common in children and viral infections are responsible for the majority of exacerbations. as leukotrienes are potent inflammatory mediators, some studies have shown that montelukast, a leukotriene receptor antagonist, may be effective on reduction of asthma symptom. to determine whether a short course of montelukast in asthmatic children with common col...

Background: There are multiple connections between sleep and lung cancer. Both of them impacting each other cancer can make it difficult to well due symptoms treatment side effects( 20-70% patients suffer insomnia) .Also there is possible relationship nocturnal intermittent hypoxia, apnea daytime sleepiness, progression considered as risk factor obstructive severity. Aim the work: evaluate patt...

the production of experimentally induced drug resistance in the laboratory provides valuable opportunities for investigators to study the nature and genetics of drug resistance mechanisms to a given agent, patterns of cross resistance and the mode of action of drugs. at the beginning the continuous drug exposure was chosen as a standard procedure to produce drug— resistant strains of p. falcipa...