background: erythropoietin (epo) is known as a regulating hormone for the production of red blood cells, called erythropoiesis. some studies have shown that epo exerts some non-hematopoietic protective effects on ischemia-reperfusion injuries in myocytes. using echocardiography, we evaluated the effect of epo infusion on reducing ischemia-reperfusion injuries and improvement of the cardiac func...

Objective- In the present study the role of essential oil of Salvia rhtidia (SR), in ameliorating renal ischemia reperfusion (IR) injuries is evaluated. Design- Experimental in vivo study. Animals- 48 male healthy Wistar rats between 250-300 grams. Procedures- The animals were randomly divided into eight groups of six rats. In ischemic groups (groups A-D), under general anesthesia b...

Introduction: This study was aimed to investigate the effects of postconditioning by natural honey on cardiac arrhythmias in the ischemic isolated rat heart. Methods: Male Wistar rats were divided into four groups then anesthetized by sodium pentobarbital. The animal hearts were removed and quickly mounted on a Langendorff apparatus and perfused under constant pressure by a modified Krebs-H...

The function of the organs responsible for detoxification processes, in particular liver, deserves a special role conditions combined trauma. It is proved that ischemia-reperfusion limb caused by imposition tourniquet, cause significant toxemia. Under such conditions, it becomes clear may be impaired, especially against background blunt trauma to abdominal complicated massive bleeding. Changes ...

myocardial infarction is a common presentation of coronary artery disease and the leading cause of death worldwide. the present study was investigated potential resistance to ischemia-reperfusion (i/r) injuries following administration of methanolic (meoh) extract of scrophularia frigida (s. frigida) in isolated rat heart. male wistar rat hearts (n= 8-10) were isolated and allowed to equilibrat...

BACKGROUND Renal ischemia reperfusion injury may occur in a variety of clinical situations, following a transient drop in total or regional blood flow to the kidney. This study was performed to investigate the protective effects of different antioxidants such as vitamin C, vitamin E, hydrocortisone and combination of these agents against experimental renal ischemia-reperfusion injury. METHOD ...

Objective(s): The aim of this study is to determine the therapeutic effects of pomegranate seed oil, which is a powerful antioxidant and anti-inflammatory agent, on ovarian-ischemia and reperfusion injury in rats.Materials and Methods: Fifty-six  female albino Wistar rats were divided into 7 equal groups. Group 1; Sham Operation, Group 2; Ischemia, Group 3; Ischemia + Reperfusion, Group 4; Isch...

Livers cold preserved during variable periods of ischemia suffer functional, morphological and hemodynamic alteration, which are exacerbated when they are reperfused. One important injury is glycogen depletion during cold ischemia/ reperfusion. How liver can restore their energy during reperfusion is related with the preservation time, nutritional status of the donor, and the preservation solut...

background: it has been reported that the chronic oral administration of garlic homogenate protected the rat heart from in vitro ischemic reperfusion injury. however, the biological effects of garlic juice on the heart are expected to be different from oral administration of it. objective: the present study was designed to investigate the effect of garlic juice on the isolated rat heart in isch...