نتایج جستجو برای: ischemic reperfusion injury

تعداد نتایج: 398121  

حق نژاد آذر, عادل, خدمتی, سهیلا, شادمان, جواد, پناهپور, حمداله,

 Background and purpose: Sesame oil (SO) is known to have antioxidant and anti-inflammatory properties and may produce protective effects against ischemic stroke-induced brain injuries. We examined the effects of treatment with SO on cerebral infarction and edema in a rat model of ischemic stroke. Materials and methods: Thirty male Sprague Dawley rats were divided into sham, ischemic, and isch...

Journal: :The Journal of surgical research 1988
M J Lynch C M Grum K P Gallagher S F Bolling G M Deeb M L Morganroth

Ischemic-reperfusion lung injury is a factor potentially limiting the usefulness of distant organ procurement for heart-lung transplantation. Toxic oxygen metabolites are considered a major etiologic factor in reperfusion injury. Although oxygen-free radicals may be generated by many mechanisms, we investigated the role of xanthine oxidase in this injury process by using lodoxamide, a xanthine ...

2009
PITCHAI BALAKUMAR MANJEET SINGH

Organ damage after reperfusion of previously viable ischemic tissues is defined as ischemia/reperfusion injury. The pathophysiology of ischemia/reperfusion injury involves cellular effect of ischemia, reactive oxygen species and inflammatory cascade. Protection against ischemia/reperfusion injury may be achieved by preconditioning or postconditioning. In this review, we discuss basic mechanisms...

Objective(s): Chronic diabetes impedes cardioprotection in reperfusion injury and hence protecting the diabetic heart would have important outcomes. In this study, we evaluated whether combined postconditioning with ischemia and cyclosporine-A can restore oxidative stress and histopathological changes in reperfusion injury of the diabetic myocardium. Materials and Methods: Streptozocin-induced ...

Journal: :iranian journal of radiology 0
xiao zhi zheng department of ultrasound, the fourth affiliated hospital of nantong university (the first people’s hospital of yancheng), jiangsu province, p.r. china bin yang department of ultrasound, jinling hospital, nanjing university school of medicine, jiangsu province, p.r. china; department of ultrasound, jinling hospital, nanjing university school of medicine, 305 east zhongshan road, 210002, nanjing city, jiangsu province, p.r.china. tel: +86-2580861314, fax: +86-2580863136 jing wu department of ultrasound, the fourth affiliated hospital of nantong university (the first people’s hospital of yancheng), jiangsu province, p.r. china

conclusion the myocardial grayscale intensity, velocity and displacement can effectively reflect the situation of steiri in patients after cardiac operation, and ti (cvi) has a higher performance in discriminating between patients with and without steiri. background the timely diagnosis of presence or absence of reperfusion injury after cardiac operation is critical for the patient’s outcome. w...

2016
Carlos Henrique Marques dos Santos Ricardo Dutra Aydos Ed Nogueira Luciana Nakao Odashiro Miiji Pedro Carvalho Cassino Isadora Ishaq Alves Nádia Meneguesso Calheiros Milena Garcia

Introduction Ischemic postconditioning is a method that shows evidence of efficacy in minimizing reperfusion injury; however, its effectiveness in preventing injuries in distant organs is still unknown, especially in those who have undergone mesenteric ischemia and reperfusion. Objective To evaluate the effect of ischemic postconditioning in preventing reperfusion injury in the liver of rats ...

2012
Shogo Shimizu Darryl T. Martin Fotios Dimitriadis Keisuke Satoh Motoaki Saito

The primary pathophysiological event in testicular torsion is ischemia-reperfusion (I-R) injury, which is caused by the twisted spermatic cord and its release. Moreover, testicular torsion is most likely mediated by reactive oxygen species. Ischemic preconditioning (IPreC) is a phenomenon in which a prior ischemic stress renders the organ resistant to a subsequent ischemic insult. Ischemic post...

Journal: :JACC. Heart failure 2015
Eric R Bates

A cute thrombotic occlusion of a coronary artery usually produces myocardial ischemia that can result in myocardial infarction if reperfusion is not restored. Reperfusion injury from reintroduction of blood and oxygen into the ischemic area at risk can result in additional myocyte cell death (1,2). Whereas early reperfusion therapy has been shown to reduce infarct size by decreasing ischemic in...

Objective(s): To study the effect of acute and repeated stress on cardioprotection-induced by remote ischemic preconditioning (RIPC).Materials and Methods: RIPC was induced by giving 4 short cycles of ischemia and reperfusion, each consisting of five min. The Langendorff’s apparatus was used to perfuse the isolated rat hearts by subjecti...

Objective(s): Renal ischemia-reperfusion injury (IRI) as a severe condition of acute kidney injury (AKI) is the most common clinical problem with high mortality rates of 35-60% deaths in hospital. Mesenchymal stem cells (MSC) due to unique regenerative characteristics are ideal candidates for the treatment of the ischemic injuries. This work is focused on the administration of MSC to IRI-induce...

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