The large-scale isolation of specific isomers of amyl alcohols for applications in the chemical, pharmaceutical, and biochemical industries represents a challenging task due to the physicochemical similarities of these structural isomers. The homochiral metal-organic framework cadmium-BINOL (BINOL=1,1'-bi-2-naphthol) is suitable for the separation of pentanol isomers, combining adsorption selec...

In this work, a theoretical framework is developed to explain and predict changes in the product distribution of the propene dimerization reaction, which yields a mixture of C6 olefin isomers, resulting from the use of different porous materials as catalysts. The MOF-74 class of materials has shown promise in catalyzing the dimerization of propene with high selectivity for valuable linear olefi...

Background: Chroman-4-one, also known as 2,3-dihydro-1-benzopyran- 4-one, is a heterocyclic compound with benzene nucleus fused to 2,3-dihydro-g-pyranone ring. The synthesis of chroman-4-one derivatives very appealing aspect in the field natural and medicinal chemistry. Materials Methods: (Z)-3-ethylidene-5,7-dimethylthiochroman- 4-one were, synthesized evaluated intended for their Monoamine ox...

naphthol isomers were simultaneously and spectrophotometrically determined in wastewater, using a model based on net analyte signal (nas). the calibration method used is a variation of the original hybrid linear analysis method as proposed by goicoechea and olivieri (hla/go). owing to spectral interferences, the simultaneous determination of mixtures of naphthol isomers, using a spectrophotomet...

alpha-Keto amides 10a,b, formed from reaction of pyruvic or benzoylformic acid with allyl amine are found to present as single rotameric forms whilst their tertiary amido analogues 10c, d present as two rotamers in solution at rt. The hydroxyimino derivatives 8 share the conformational characteristics of their parents. The geometrical make-up of the new alpha-amidooximes is seen to depend on th...

The synthesis of "rim-differentiated" C5-symmetric pillar[5]arenes, whose two rims are decorated with different chemical functionalities, has remained a challenging task. This is due to the inherent statistical nature of the cyclization of 1,4-disubstituted alkoxybenzenes with different substituents, which leads to four constitutional isomers with only 1/16th being rim-differentiated. Herein, w...

The preparation and characterization of p-tert-butylcalix[4]arene-1,3-bis(allyloxyethoxy)ether (CA[4]-BAE) chemically coated capillaries via a free-radical reaction with vinyltriethoxysilane (VTES) that was attached onto the inner wall previously were carried out. IR spectra and decreased electroosmotic flow (EOF) suggested that the capillary was successfully coated with CA[4]-BAE. A slight slo...

To understand the structural features that dictate the selectivity of the two isoforms of the prostaglandin H2 synthase (PGHS/COX), the three-dimensional (3D) structure of COX-1/COX-2 was assessed by means of binding energy calculation of virtual molecular dynamic with using ligand alpha-Patchouli alcohol isomers. Molecular interaction studies with COX-1 and COX-2 were done using the molecular ...

Introduction Lipids play a key role in cell, tissue, and organ physiology. Many diseases, such as cancer and diabetes, involve disruption of their metabolic enzymes and pathways. Identification of unique lipid biomarkers to distinguish healthy humans compared to those with a disease can have an impact on the early detection of diseases and personalized medicine. Because of the complexity of a l...