The emergence of carbapenemase-producing Klebsiella pneumoniae (CPKP) has become a great concern worldwide. In this study, 994 non-duplicate, carbapenem non-susceptible Klebsiella pneumonia isolates were collected in Taiwan from 2011 to 2013 for detection of the carbapenemase genes, assessment of antimicrobial susceptibility and molecular epidemiology studies. Of these 994 isolates, 183 (18.4%)...

A new commercial low-density microarray which identifies common extended-spectrum β-lactamase plasmid-mediated cephalosporinase genes, as well as carbapenemase (bla(KPC) and bla(NDM)) genes, was evaluated. We tested 207 clinical and reference/collection isolates of the Enterobacteriaceae possessing different bla genes. Overall, the sensitivity and specificity of the microarray were 100% for the...

we study harmonic analysis on cocommutative kpc-hyper-groups‎, which is a generalization of djs-hypergroups‎, ‎introduced by kalyuzhnyi‎, ‎podkolzin and chapovsky‎. ‎we prove that there is a relationship between‎ ‎the associated measures $mu$ and $gamma mu$‎, ‎where $mu$ is‎ ‎a radon measure on kpc-hypergroup $q$ and $gamma$ is a character on $q$.

Ceftazidime–avibactam (CAZ-AVI) is an active antibiotic combination of a β-lactam–β-lactamase inhibitor against carbapenemase-producing Enterobacterales. Reports resistance to CAZ-AVI other than metallo-β-lactamases have increased in recent years. The aim this study was analyze KPC-Klebsiella pneumoniae (KP) isolates resistant from the intestinal carriage hospitalized elderly patients Italy, Fe...

the emergence of multidrug resistance (mdr) and extensively drug resistance (xdr) in acinetobacter baumannii has made an important challenge in the treatment of infections caused by this organism. the ability of carbapenemase production is one of the main mechanisms for the emergence of mdr and/or xdr in a. baumannii. the aim of this study was to detect carbapenemase producer a. baumannii. in t...

We study harmonic analysis on cocommutative KPC-hyper-groups‎, which is a generalization of DJS-hypergroups‎, ‎introduced by Kalyuzhnyi‎, ‎Podkolzin and Chapovsky‎. ‎We prove that there is a relationship between‎ ‎the associated measures $mu$ and $gamma mu$‎, ‎where $mu$ is‎ ‎a Radon measure on KPC-hypergroup $Q$ and $gamma$ is a character on $Q$.

OBJECTIVES KPC-possessing Klebsiella pneumoniae have been found to be widespread in several regions but are still rarely detected in Europe. We describe the characteristics of an outbreak caused by KPC producers in a tertiary care Greek hospital. METHODS During a 12 month period (October 2007-September 2008), 47 patients in Hippokration University Hospital yielded K. pneumoniae isolates that ...

OBJECTIVES To perform molecular epidemiology for 113 KPC-producing Klebsiella pneumoniae isolated in 2010 from 12 Brazilian states. METHODS The resistance profile was determined by disc diffusion and Etest. Genetic polymorphism was analysed by PFGE and multilocus sequence typing. The genetic environment of the bla(KPC) gene was determined by PCR and identification of the carrier plasmid was d...

A Klebsiella pneumoniae isolate showing moderate to high-level imipenem and meropenem resistance was investigated. The MICs of both drugs were 16 microg/ml. The beta-lactamase activity against imipenem and meropenem was inhibited in the presence of clavulanic acid. The strain was also resistant to extended-spectrum cephalosporins and aztreonam. Isoelectric focusing studies demonstrated three be...