It has been suggested that ice cores may preserve detectable enhancements of some terrestrially rare radioisotopes, Be, Al, Cl, resulting from a near-Earth core-collapse supernova(SN) [1]. Both Be and Cl are also produced by atmospheric cosmic ray spallation and hence are influenced by processes that modulate the Earth’s cosmic ray flux. Previous studies [2], [3] have suggested that enhancement...

a Department of Physics and Astronomy, University of Louisville, Louisville 40292, KY, United States b Department of Materials Science & Engineering, Iowa State University, Ames 50011, IA, United States c Department of Chemical Engineering, University of Louisville, Louisville 40292, KY, United States d Conn Center for Renewable Energy Research, University of Louisville, Louisville 40292, KY, U...

Graduate Center for Toxicology, University of Kentucky, Lexington, KY 40536, USA Faculty of Medicine, Prince of Songkla University, Songkhla, Thailand Department of Chemistry, Center of Membrane Sciences, and Sanders-Brown Center on Aging, 121 Chemistry-Physics Building, University of Kentucky, Lexington, KY 40506, USA Department of Physiology, University of Kentucky, Lexington, KY 40536, USA D...

Adaptation to environmental stress requires genome-wide changes in gene expression. Histone modifications are involved in gene regulation, but the role of histone modifications under environmental stress is not well understood. To reveal the relationship between histone modification and environmental stress, we assessed the effects of inhibitors of histone modification enzymes during salinity s...

Reactive oxygen species are damaging to cardiomyocytes. H9c2 cardiomyocytes are commonly used to study the cellular mechanisms and signal transduction in cardiomyocytes, and to evaluate the cardioprotective effects of drugs following oxidative damage. The present study developed a robust, automated high throughput screening (HTS) assay to identify cardioprotective agents from a traditional Chin...

1Department of Mechanical Engineering, University of Louisville, 200 Sacket Hall, Louisville, KY 40292, USA 2The Electrooptics Research Institute and Nanotechnology Center, University of Louisville, Louisville, KY 40292, USA 3Department of Biomedical Engineering, University of Wisconsin-Madison, 6036 WIMR, 1111 Highland Avenue, Madison, WI 53705, USA 4Department of Bioengineering, University of...

Woolly mammoths inhabited Eurasia and North America from late Middle Pleistocene (300 ky BP [300,000 years before present]), surviving through different climatic cycles until they vanished in the Holocene (3.6 ky BP). The debate about why the Late Quaternary extinctions occurred has centred upon environmental and human-induced effects, or a combination of both. However, testing these two hypoth...

In this paper, a new transformerless buck-boost converter based on ZETA converter is introduced. The proposed converter has the ZETA converter advantages such as, buck-boost capability and input to output DC insulation. The suggested converter voltage gain is higher than the classic ZETA converter. In the presented converter, only one main switch is utilized. The proposed converter offers low v...