background: hemoptysis occurs due to either pulmonary diseases or bronchoscopy interventions. the aim of the present study was to compare the efficacy of the endobronchial instillation of adrenaline with that of tranexamic acid. methods: fifty patients were randomly selected as 2 double-blinded sample groups (n=25). in these patients, bleeding could not be controlled with cold saline lavage dur...

The aim of the study was to assess the efficacy, safety and complications of two anesthetic techniques including local and spinal anesthesia. A total of 436 patients received local (LA group = 250) or spinal (SA group = 186) anesthesia during a year period. SA group received 0.5% Bupivacaine 5 mg/mL. LA group received portal injection (5 mL lidocaine 2% with adrenaline) and intra-articular inje...

The present study was designed to assess the efficacy of fentanyl and pancuronium combined with dilute lidocaine solution for axillary block. Onehundred adult patients undergoing upper limb surgery were randomly allocated to receive either 0.6 mL/kg of 1 % lidocaine (6 mg/kg) or 0.6 mLlkg of 0.5% lidocaine (3 mg/kg) with 1 µg/kg of fentanyl and 0.5 mg of pancuronium. The onset of sensory a...

OBJECTIVE To evaluate the results and complications from surgical treatment of carpal tunnel syndrome by means of an open route, using a local anesthesia technique comprising use of a solution of lidocaine, epinephrine and sodium bicarbonate. MATERIAL AND METHODS This was a cohort study conducted through evaluating the medical files of 16 patients who underwent open surgery to treat carpal tu...

OBJECTIVES To characterize the uptake, washout, and metabolism of lidocaine hydrochloride in the iris/ciliary body and cornea. METHODS Iris/ciliary body uptake of lidocaine hydrochloride was measured by incubating human and rabbit irides in radiolabeled carbon 14-1% lidocaine hydrochloride for 2 to 60 minutes. Washout was determined by incubating the iris in 14C-1% lidocaine hydrochloride for...

BACKGROUND One-per-mil tumescent solution, which contains 0.2% lidocaine with 1:1,000,000 epinephrine, has been reported to be clinically effective for hand surgery under local anesthesia. However, it was lacking in its basic pharmacokinetics profile in regard to the onset of action (OOA) and duration of action (DOA). METHODS A randomized, double-blind study was conducted on 12 volunteers who...

Previous studies have reported a decreased incidence of delayed graft function after cadaveric transplantation with the use of lidocaine pretreatment of the donor. We evaluated the effects of lidocaine on prolonged cold ischemia and reperfusion injury in a canine model of isolated kidney perfusion (IPK). The purpose of this study was to evaluate the renal function of isolated perfused canine ki...

Effects of adrenaline on the smooth muscle of the rabbit common carotid artery were studied by the partitional chamber method. The experiments on excitation-contraction coupling were carried out in isotonic Krebs solution; the other experiments were carried out in hypertonic Krebs solution. Adrenaline (10(-7) g/ml) caused rhythmical electrical and mechanical activity of arterial strips in isoto...

this blinded, randomized experimental study was designed to evaluate the analgesic effects of adding epinephrine or xylazine to lidocaine solution for brachial plexus block (bpb) in sheep. nine healthy, fat-tailed female lambs (26.6 ± 1.5 kg) were randomly allocated into three groups: lidocaine 2%, 5 mg kg-1 (lid, n = 6), lidocaine (5 mg kg-1) with epinephrine 5 µg ml-1 (lidep, n = 6) or lidoca...