Present review describes research on novel natural pharmacological compounds isolated from marine sponges. More than 90 novel cytotoxic antitumor compounds and their synthetic analogs have shown confirmed activity in vitro tumor cell lines bioassay and are of current interest to NCI for further in vivo evaluation. A great problem, to use directly the reservoir of marine organisms for therapy is...

For the past few centuries, the biological sources of terrestrial origin have been explored and exploited for bioactive metabolites. This has resulted in the stagnancy of discovering either novel compounds or compounds with novel bioactivities. Thus, researchers across the globe have started exploring our big Oceans, for the search of bioactive metabolites. During the past few decades, the rese...

The main problem in the treatment of infectious diseases caused by pathogenic microorganisms is the emergence of the multi-drug resistant (MDR) pathogens. This issue has become an important focus of researches on new bioactive compounds. According to Murniasih, the development of new medicines derived from marine biota is attracting researchers attention due to the very high marine biodiversity...

Marine microorganisms continue to be a source of structurally and biologically novel compounds with potential use in the biotechnology industry. The unique physiochemical properties of the marine environment (such as pH, pressure, temperature, osmolarity) and uncommon functional groups (such as isonitrile, dichloroimine, isocyanate, and halogenated functional groups) are frequently found in mar...

Marine algae are known to contain a wide variety of bioactive compounds, biomaterials derived from marine algae have commercial applications in pharmaceutical, medical, cosmetic, nutraceutical, food and agricultural industries. Marine algae are found to contain high amount of nutrients, vitamins (A, B, C, D & E), minerals (Ca, P, Na & K), antioxidants and dietary fibers, that’s why they are use...

the antibacterial and antioxidant activities of methanol and acetone extracts of three marine algae, including hypnea hamulosa, gracilaria corticata and enteromorpha intestinalis wereinvestigated.antioxidant activities were determined by means of total antioxidant capacity, total phenolic compounds, dpph radical scavenging activity and ferric reducing antioxidant power. antibacterial activity w...

Knowledge on the effects of pharmaceuticals on aquatic marine ecosystems is limited. The aim of this study was therefore to establish the effect thresholds of pharmaceutical compounds occurring in the Belgian marine environment for the marine diatom Phaeodactylum tricornutum, and subsequently perform an environmental risk assessment for these substances. Additionally, a screening-level risk ass...