Background and Objective: Integrons play an essential role in disseminating drug resistance genes among bacteria. The aim of this study was to determine the prevalence of integrons, and Extended-Spectrum β-Lactamase (ESBL) genes in Escherichia coli (E. coli) isolates collected from patients with urinary tract infection (UTI) referred to teaching hospitals in Ardabil, Iran. Materials and Method...

OBJECTIVES Horizontal transfer of integrons is one of the important factors that can contribute to the occurrence of multidrug-resistant (MDR) bacteria. This study aimed to determine the prevalence of integrons among MDR Escherichia coli strains isolated from stool specimens and investigate the associations between the existence of integrons and MDR properties in the southwest of Iran. METHOD...

TO THE EDITOR—We read with interest the article by Johnson et al, which demonstrates that, in extraintestinal pathogenic Escherichia coli (ExPEC), fluoroquinolone (FQ) resistance is currently associated with the rapid expansion of a single dominant multidrug-resistant (MDR) strain that emerged within sequence type (ST) 131 [1]. Although the strong predominance of the ST131 clone has been well d...

INTRODUCTION Increasing resistance in Escherichia coli and Klebsiella pneumoniae to firstline antibiotics makes therapeutic options for urinary tract infections (UTIs) challenging. This study investigated the in vitro efficacies of 6 antibiotics against multidrug resistant (MDR) uropathogens. MATERIALS AND METHODS Minimum inhibitory concentrations to ceftibuten, cefpodoxime, fosfomycin, mecil...

BACKGROUND Antimicrobial resistance among pathogenic Escherichia coli is an increasing problem especially in developing countries. AIMS To compare between resistance patterns of E. coli collected from two unrelated geographical areas. METHODS A descriptive comparative study was conducted between May 2010 and August 2011. E. coli (n= 402) collected from hospitals in Khartoum state, Sudan and...

AIM The study evaluates the microbial as well as physicochemical pollution of groundwater of Brij region of Uttar Pradesh, a major tourist destination in the country along with estimating the drug resistance evident in the isolated Escherichia coli. MATERIALS AND METHODS A total of 60 samples of groundwater were collected from six different sites and assessed for physicochemical (pH, color, t...

OBJECTIVES In 2013, Clermont classified E. coli strains into eight phylogenetic groups using a new quadruplex PCR method. The aims of this study were to identify the phylogenetic groups of E. coli based on this method and to assess their antibiotic resistance patterns in Bushehr, Iran. METHODS In this cross-sectional study, 140 E. coli isolates were subjected to phylogenetic typing by a quadr...

Urinary tract infection (UTI) is the leading cause of death among patients and majority people visiting hospital worldwide. In current quantitative study, urine samples were obtained using sterile method 100 isolates, including 60 Escherichia coli, 28 Klebsiella sp., 12 Proteus investigated in a laboratory. Current study showed that E. coli 60/100 (60%) was most common UTI followed by sp. 28/10...

INTRODUCTION Fresh produce has been implicated in a number of documented outbreaks of foodborne illness caused by bacteria, viruses, and parasites. Shiga toxin-producing Escherichia coli (STEC) have been detected on vegetables, raising concerns about the prevalence of E. coli contamination in produce, which can take place at various points from farm to fork. This study aimed to detect the prese...

The human MDR1 gene is induced by cadmium exposure although no resistance to this metal is observed in human cells overexpressing hMDR1. To access the role of MDR proteins in cadmium resistance, human MDR1, Lactococcus lactis lmrA, and Oenococcus oeni omrA were expressed in an Escherichia coli tolC mutant strain which proved to be hypersensitive to cadmium. Both the human and bacterial MDR gene...