Allium Jesdianum (AJ) is the native plant mostly grown in Middle East region that has the excellent pharmacological properties. In this study, we evaluated the hepatoprotective effect of hydroalcoholic extract of AJ on liver injury induced by Bromobenzene (BB) in male mice. Animals were randomly divided into five groups, control group received normal saline plus olive oil, groups 2-4 received(5...

background in the living donor liver transplant setting, the preoperative assessment of potential donors is important to ensure the donor safety. objectives the aim of this study was to identify causes and costs of living liver-donors rejection in the donation process. materials and methods from june 2010 to june 2012, all potential living liver donors for 66 liver transplant candidates were sc...

5-Aminolevulinic acid (ALA) is the rate-limiting intermediate in heme biosynthesis vertebrate species; a reaction catalyzed by mitochondrial ALA synthase 1 (ALAS1) enzyme. Previously we reported that knockdown of ubiquitously expressed ALAS1 gene mice disrupts normal glucose metabolism, attenuates function and results prediabetic like phenotype when animals pass 20-weeks age (Saitoh et al., 201...

Glavonoid-rich oil (GRO) derived from ethanol extraction of licorice (Glycyrrhiza glabra Linne) root has been reported to have beneficial effects on health. In this study, we aimed determine the effect long-term administration GRO metabolic disorders and elucidate molecular mechanism. Female obese, type 2 diabetic KK-Ay mice were fed diets supplemented with 0.3% or 0.8% (w/w) for 4–12 weeks. Mi...

Background: Diabetes produces free radicals and damages the liver. The aim of this study was to investigate the effects of Rosmarinus Officinalis leaf hydroalcoholic extract on histopathology and enzymes activity of liver in alloxan induced diabetic rats. Methods: In this study, 50 adult male Wistar rats weighing 200 to 250 grams, were divided randomly into 5 groups of 10; non-diabetic control...

Background: Exposure to ionizing radiation is inevitable. Using of low-level laser therapy (LLLT) stimulates tissue repair and reduces inflammation. The objective of the present study aimed at evaluating the therapeutic efficacy of Helium-Neon (He-Ne) laser in stimulating the reparative processes in the liver of mice after whole body gamma-irradiation (WBγ-I). Materials and Methods: Two hundred...

introduction dendritic cells (dcs) are bone marrow-derived cells, which migrate to lymphoid and non-lymphoid organs via blood. liver dcs are believed to play an important role in the regulation of hepatic allograft acceptance. however, because of inherent difficulties in isolating adequate numbers of dcs from liver, limited information is available on the phenotype and functions of liver dcs. t...