Azin Samimi

Department of Pharmacology and Toxicology, Pharmacy School, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran

[ 1 ] - Prevalence of Symptoms in Patients Poisoned with Iranian Crack in Ahvaz Razi Hospital in 2008-2013

Background: Crack is a strong and smoking form of cocaine, but Iranian crack is different from common crack cocaine, having symptoms and side effects similar to those of heroin. This study was to investigate the prevalence and clinical symptoms in patients poisoned with Iranian crack poisoning hospitalized in Ahvaz Razi Hospital in the years 2008-2013. Methods: In this study, 63 subjects with I...

[ 2 ] - Efficiency of naringin against reproductive toxicity and testicular damages induced by bisphenol A in rats

Objective(s): Bisphenol A (BPA) as a synthetic compound is applied in many plastic industries. BPA has been reported to have endocrine-disrupting feature with cytotoxic effects. The study aimed to evaluate the efficiency of Naringin against testicular toxicity induced by BPA in adult rats.Materials and Methods: The animals were assigned into six groups of control, BPA-treated (50 mg/kg), BPA+Na...

[ 3 ] - Histopathological and Biomedical parameters Determination in the Protective Effect of Hydroalcoholic Extract of Allium Jesdianum on Hepatotoxicity Induced by Bromobenzene in Mice

Allium Jesdianum (AJ) is the native plant mostly grown in Middle East region that has the excellent pharmacological properties. In this study, we evaluated the hepatoprotective effect of hydroalcoholic extract of AJ on liver injury induced by Bromobenzene (BB) in male mice. Animals were randomly divided into five groups, control group received normal saline plus olive oil, groups 2-4 received(5...

[ 4 ] - Evaluation the protective effects of doxycycline on acetaminophen-induced hepatotoxicity in mice

Acetaminophen (APAP) toxicity threatens human health due to increased mortality associated with its overdose. Doxycycline (DC) because of its properties such as antioxidant and anti-inflammatory can be a good therapeutic strategy to treat the acute toxicity induced by APAP. Male mice were divided to six groups in two periods of 3 and 24-h as normal saline, APAP 400 mg/kg, DC 100 mg/kg and group...

[ 5 ] - Evaluation the protective effects of doxycycline on acetaminophen-induced hepatotoxicity in mice

Acetaminophen (APAP) toxicity threatens human health due to increased mortality associated with its overdose. Doxycycline (DC) because of its properties such as antioxidant and anti-inflammatory can be a good therapeutic strategy to treat the acute toxicity induced by APAP. Male mice were divided to six groups in two periods of 3 and 24-h as normal saline, APAP 400 mg/kg, DC 100 mg/kg and group...