Leila Zeidooni

Department of Pharmacology and Toxicology, Pharmacy School, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran

[ 1 ] - Efficiency of naringin against reproductive toxicity and testicular damages induced by bisphenol A in rats

Objective(s): Bisphenol A (BPA) as a synthetic compound is applied in many plastic industries. BPA has been reported to have endocrine-disrupting feature with cytotoxic effects. The study aimed to evaluate the efficiency of Naringin against testicular toxicity induced by BPA in adult rats.Materials and Methods: The animals were assigned into six groups of control, BPA-treated (50 mg/kg), BPA+Na...

[ 2 ] - Evaluation the protective effects of doxycycline on acetaminophen-induced hepatotoxicity in mice

Acetaminophen (APAP) toxicity threatens human health due to increased mortality associated with its overdose. Doxycycline (DC) because of its properties such as antioxidant and anti-inflammatory can be a good therapeutic strategy to treat the acute toxicity induced by APAP. Male mice were divided to six groups in two periods of 3 and 24-h as normal saline, APAP 400 mg/kg, DC 100 mg/kg and group...

[ 3 ] - Hydroalcoholic extract of Iranian Caper leaves protects hepatic toxicity by suppressing oxidative stress in mice

Capparis spinosa L. (Caper) is known as an aromatic plant, commonly used in Mediterranean diet, possessing numerous antioxidant compounds such as phenols, rutin, tocopherols, carotenoids, and vitamin C in its leaves. Thus, the purpose of the present study was to investigate the effects of Iranian Caper leaves extract on oxidative stress caused by CCl4 in mice liver. In this study, a total numbe...