A new method of preparing ionically cross-linked polyphosphazene hydrogel microspheres which enables effective control over microsphere size distribution has been developed. The synthesized microspheres can be used in protein delivery and, especially, as vaccine delivery vehicles. A new technique utilizes the ability of aqueous solutions of poly[di(carboxylatophenoxy)phosphazene] (PCPP) to form...

Microencapsulating stem cells in injectable microbeads can enhance delivery and localization, but their ability to act as growth factor production sources is still unknown. To address this concern, growth factor mRNA levels and production from alginate microbeads with encapsulated human adipose stem cells (ASC microbeads) cultured in both growth and chondrogenic media (GM and CM) were measured ...

Essential oils are natural liquid products obtained from plants by hydroor steam distillation. Oils contain from dozens to hundreds of components – secondary plant metabolites. The essential oils are used as natural aromas in food and toiletry, and due to medicinal properties, many of them are used in conventional medicine and aromatherapy. Components of the essential oils are first of all mono...

During the W1/O phase (in the W1/O/W2 process) of protein microencapsulation within poly-lactide-co-glycolide (PLGA), hydrophobic interfaces are expanded where interfacial adsorption occurs followed by protein unfolding and aggregation. Spectroscopic and immunological techniques were used to ascertain the effects of the Hoffmeister series ions on Diphtheria toxoid (Dtxd) stability during the W1...

Functional foods are beginning to play a major role in what consumers buy and eat. The International Life Science Institute has defined a functional food as ‘a food which has a beneficial effect on one or more target functions of the body, above and beyond the usual effects of food, such as improving the state of health and well-being or reducing the risk of disease. Examples of these types of ...

The Effect of Different Sources Selenium and Microencapsulation on Fertility Hatching Traits in Arbor Acres Broiler Breeder

The formulation of natural substances together with a biocompatible or biodegradable carrier material to form composites or encapsulates has a great relevance for pharmaceutical, cosmetic and food industries. The main objective of this article is taking a look at microencapsulation as a novel drug delivery system. Its scope extends beyond conventional microcapsules to all other small particulat...

The microencapsulation of tuna oil in gelatin-sodium hexametaphosphate (SHMP) using complex coacervation was optimised for the stabilisation of omega-3 oils, for use as a functional food ingredient. Firstly, oil stability was optimised by comparing the accelerated stability of tuna oil in the presence of various commercial antioxidants, using a Rancimat™. Then zeta-potential (mV), turbidity and...

Beta-carotene is the main dietary source of Vitamin A, an essential micronutrient required to maintain proper health. The in vivo bioavailability and absorption of beta-carotene, however, is limited due to the inhibition by the natural plant matrices in which it is found. This study focused on microencapsulation methods to improve release and bioavailability in vitro. Alginate and chitosan form...

The successful implementation of human embryonic stem cells (hESCs)-based technologies requires the production of relevant numbers of well-characterized cells and their efficient long-term storage. In this study, cells were microencapsulated in alginate to develop an integrated bioprocess for expansion and cryopreservation of pluripotent hESCs. Different three-dimensional (3D) culture strategie...