OBJECTIVE Offspring of bipolar parents have a genetically increased risk of developing mood disorders. In a longitudinal study, the authors followed a bipolar offspring cohort from adolescence into adulthood to determine the onset, prevalence, and early course of mood disorders and other psychopathology. METHOD The Dutch bipolar offspring cohort is a fixed cohort initiated in 1997 (N=140; age...

OBJECTIVE Comorbid bipolar and panic disorders aggregate in families. A phenotypic trait shared by both disorders is the sudden shift in affect observed in panic attacks and some rapid cycling states. The authors investigated whether comorbidity of bipolar disorder and panic disorder is associated with rapid mood switching in families with a high rate of bipolar disorder. METHOD Six hundred s...

BACKGROUND Individuals with bipolar disorder often endorse dysfunctional beliefs consistent with cognitive models of bipolar disorder (Beck, 1976; Mansell, 2007). AIMS The present study sought to assess whether young adult offspring of those with bipolar disorder would also endorse these beliefs, independent of their own mood episode history. METHOD Participants (N = 89) were young adult co...

conduct disorder is a general psychiatric classification encompassing a variety of behavior patterns in which the individual repetitively and persistently violates the rights, privilages and privacy of others, for these children and adolescents, the authority figures like parents and teachers are assumed as intervening and punishing individuals, some of these patients are diagnosed as having at...

Bipolar disorder is a brain illness that causes mood, energy, and ability to function variations. patients have extreme emotional states often occur over period of days weeks, referred as mood episodes. Manic/hypomanic (abnormally cheerful or angry mood) depressed (sad episodes are classified. People with bipolar frequently periods neutral mood. can live long productive lives if they treated. T...

Neuroleptic induced neurological side effects were compared over a period of one year (1991-1992) in 45 schizophrenics and age and sex matched 42 mood disorder patients, diagnosed as per DSM-III-R criteria. Prevalence of dystonia was equally common in both groups. Pseudoparkinsonism was significantly high in female mood disorder patients, akathisia in middle aged mood disorder patients and trad...

Objective. The aim of the present study is to evaluate the link between the age of onset of mood disorders and the complexity of the personality traits. Methods. 209 patients with major depressive or manic/hypomanic episodes were assessed using the Structured Clinical Interview for DSM Axis I diagnoses and the Millon Clinical Multiaxial Inventory-III (MCMI-III). Results. 17.2% of the patients h...

This study investigated the possibility that, in remitted bipolar I affective disorder, dysfunctional attitudes are mood-state dependent. Participants were 120 individuals with remitted bipolar I disorder, remitted unipolar depression, or no history of affective disorder. The Dysfunctional Attitudes Scale (DAS; Weissman, 1979) was completed before and after positive or negative mood challenge. ...

This review examines the extent to which neurological signs are more prevalent in schizophrenia patients, compared to mood-disorder patients and healthy subjects, and whether there is a pattern in any of the differences that may be found. We included 17 studies and calculated the weighted mean prevalence of 30 neurological signs. The prevalence of most signs appears to be significantly differen...