BACKGROUND The Bipolarity Index is a clinician-rated scale that rates cardinal features of the disorder across five domains: signs and symptoms, age of onset, course of illness, response to treatment, and family history. We tested the Index in routine clinical practice to identify the optimal cut-off for distinguishing bipolar from non-bipolar disorders. METHOD Sequential patients in a privat...

BACKGROUND Pediatric screening enables the prevention or early detection of diseases and developmental disturbances in infancy and childhood. Screening is a standard component of pediatric practice in many countries, but its scientific basis is not well known. METHODS The scientific justification for pediatric screening beyond the neonatal period is presented on the basis of a selective revie...

OBJECTIVE To compare and analyze the clinical characteristics of children with delayed language acquisition due to two different diagnoses, which were specific language impairment (SLI, a primarily delayed language development) and global developmental delay (GDD, a language delay related to cognitive impairment). METHODS Among 1,598 children who had visited the developmental delay clinic fro...

UNLABELLED This study aims to examine the association of frontal functioning with subclinical bipolar spectrum by a newly developed convenient method. We investigated subclinical bipolar tendency and frontal lobe activation during word productions using multi-channel near infrared spectroscopy. PARTICIPANTS 44 healthy university students (mean ages 20.5 years old, and 29 female) gave their wr...

BACKGROUND According to some studies, almost 40% of depressive patients - half of them previously undetected - are diagnosed of bipolar II disorder when systematically assessed for hypomania. Thus, instruments for bipolar disorder screening are needed. The Mood Disorder Questionnaire (MDQ) is a self-reported questionnaire validated in Spanish in stable patients with a previously known diagnosis...

PURPOSE This study aimed to establish 1) whether a group difference exists in the motor competence of preschool children at risk for developmental delays with intelligence quotient discrepancy (IQD; refers to difference between verbal intelligence quotient [VIQ] and performance intelligence quotient [PIQ]) and 2) whether an association exists between IQD and motor competence. METHODS Children...

ôbjective: the mood disorder questionnaire (mdq) has been developed as a self-reporting, brief, and easy-to-use screening instrument to improve identification of bipolar mood disorders. the goals of the present study were to examine the prevalence of this disorder and interrelationship of its symptoms by factor analysis of mdq in a group of pregnant women in ïran. methods: ône thousand and eigh...

CONTEXT Long-term follow-up data on cognitive and motor functioning in adult patients with congenital hypothyroidism, diagnosed by neonatal screening, are scarce. Hence, it is still unclear whether the frequently reported cognitive and motor deficits observed during childhood persist in adulthood. OBJECTIVE The objective of this study was to examine cognitive and motor functioning in young ad...