Rett syndrome (RS) is a neurodevelopmental infantile disease characterized by an early normal psychomotor development followed by a regression in the acquisition of normal developmental stages. In the majority of cases, it leads to a sporadic mutation in the MECP2 gene, which is located on the X chromosome. However, this syndrome has also been associated with microdeletions, gene translocations...

Trisomy 9 is a rare chromosome disorder with high neonatal mortality. It is often seen in mosaic form. Most patients who survive are severely mentally retarded. The main features of this syndrome are "bulbous" nose, microphthalmia, dislocated limbs, and other anomalies of skeletal, cardiac, genitourinary, and central nervous system. Most patients have developmental and cognitive impairment. Pat...

background: prematurity is the most common cause of death and disability and preterm infants, are prone to developmental complications. for this reason this study was designed for follow up of these babies until 2 years by modified ddst-2. methods: this study was a prospective longitudinal descriptive study from march 2009 to march 2011 in clinic of sheikh and imam reza hospitals, mashhad, iran...

how to cite this article: najafi r, hashemipour m, mostofizadeh n, ghazavi mr, nasiri j, shahsanai a, famori f, najafi f, moafi m. demographic and clinical findings in pediatric patients affected by organic acidemia. iran j child neurol. spring 2016; 10(2): 74-81. abstract objective metabolic disorders, which involve many different organs, can be ascribed to enzyme deficiency or dysfunction and...

how to cite this article: ashrafzadeh f, sadrnabavi a, akhondian j, beiraghi toosi m, mohammadi mh, hassanpour k. angelman syndrome: a case report. iran j child neurol. spring 2016; 10(2):86-89. abstract objective angelman syndrome (as) is a neurodevelopmental disorder presented by jerky movement, speech delay and cognitive disability epilepsy as well as dysmorphic features. it occurs due to an...

how to cite this article: momen aa. momen m. double cortex syndrome (subcortical band heterotopia); a case report. iran j child neurol. 2015;9(2):64-68. abstract objective approximately 5–10% of preschool age children are considered developmentally disabled. brain magnetic resonance imaging (mri) plays a key role in the diagnostic evaluation in these children. many congenital or acquired brain ...

objectives: developmental coordination disorder (dcd) is a motor skill disorder which impacts upon a child, s ability to perform age-appropriate activity of daily living and academic performance. they have problems in gross & fine motors, their upper limb coordination are impaired, too. in this way, we decided to compare motors skills with botmp test in children with dcd and their normal peers....