Abstract An efficient multicomponent sequential process, which occurs in mild condition has been exploited for the synthesis of systematically modified amphiphilic molecules where cationic head is tethered to a lipophilic tail through dihydroorotic acid linker. The process operatively simple, high yielding, and flexible. Such strategy could impact combinatorial wide libraries be tested as trans...

an extremely facile and efficient procedure which has been developed for the synthesis of dihydropyrrol-2-ones. one-pot four-component reaction of amines, dialkyl acetylenedicarboxylates and formaldehyde in the presence of n,n,n,n-tetramethylguanidinium acetate [tmg][ac] in methanol at ambient temperature provides substituted dihydropyrrol-2-ones in good to high yields. the important aspects of...

Silica Vanadic Acid, SVA, (oxo-vanadium has been supported on silica) as a dual Lewis and Bronsted acid ability was prepared and efficiently catalyzed one-pot multi-component condensation of enolizable ketones or alkyl acetoacetates with aromatic aldehydes, acetonitrile and acetyl chloride. The described reaction was produced β-acetamido ketone or ester derivatives in high to excellent yields i...

In this research, SO3H-functionalizedphthalimide (SFP) has been prepared through simple reaction of phthalimide with chlorosulfonic acid, and characterized using FT-IR, 1H NMR, 13C NMR, SEM (scanning electron microscopy), mass and TG (thermal gravimetric) spectra. Afterward, the solid acid has been utilized as an efficient, green, heterogeneous and recyclable ca...

Amidoalkyl-2-naphthols as synthetic intermediates play an important role in medicinal chemistry due to their remarkable biological and many pharmacological properties. Owing to the versatile biological activities, industrial and synthetic applications of these compounds, introduction of an alternative methodology is urgent in synthetic organic chemistry. Low yield and harsh reaction conditions ...