compound action potential (cap) of spinal cord represents valuable properties of neural fibers including excitability, rate of myelination and membrane integrity. these properties are measured using amplitude, latency and area under curve of caps recorded from spinal cord. here, the isolated spinal cord was set in a double sucrose gap (dsg) chamber and its response to intracellular stimulation ...

Medullated, or myelinated nerve fibers affect between 0.57 to 1% of the population. They are formed by myelination of ganglion cells beyond the lamina cribrosa during embryonic development. Typically, significant visual acuity loss is uncommon. However, reports of amblyopia associated with myelinated nerve fibers have been reported in the ophthalmologic

A silver impregnation method is described which shows motor and sensory nerves and their endings in formalin-fixed mammalian muscles. The method works with the same reliability on flattened muscle pieces as well as on frozen sections. Large nerve bundles, myelinated and non-myelinated single axons, and terminals impregnated by this method stand out black against a light brown background.

Two variants of ankyrin have been distinguished in rat brain tissue using antibodies: a broadly distributed isoform (ankyrinB) that represents the major form of ankyrin in brain and another isoform with a restricted distribution (ankyrinR) that shares epitopes with erythrocyte ankyrin. The ankyrinR isoform was localized by immunofluorescence in cryosections of rat spinal cord gray matter and my...

We have examined the effects of acrylamide on primary sensory nerve cell bodies and their myelinated axons in chronic acrylamide intoxication. The numbers and sizes of dorsal root ganglion cell bodies (L5) and myelinated nerve fibers were estimated with sterelogical techniques in severely disabled rats which had been treated with 33.3 mg/kg acrylamide twice a week for 7.5 weeks. There was no lo...

The entire length of myelinated axons is organized into a series of polarized domains that center around nodes of Ranvier. These domains, which are crucial for normal saltatory conduction, consist of distinct multiprotein complexes of cell adhesion molecules, ion channels, and scaffolding molecules; they also differ in their diameter, organelle content, and rates of axonal transport. Juxtacrine...

In this paper we focus on the two particular properties of myelinated neuron, the increased conduction speed and changeable excitability. First we implemented myelinated neuron using NEURON simulator and verified in simulation the previously known two properties mentioned above. Next we tried to identify in simulation which channels were responsible for changeable excitability. Finally we verif...