Early detection of acute myocardial ischemia is critical to prevent permanent myocardial damage. The impact of apical ischemia on global left ventricular (LV) function can be difficult to characterize using traditional volume-based echocardiography measures. Myocardial strain imaging is a sensitive, quantitative marker of myocardial deformation that can measure ventricular function. Recent adva...

MYOCARDIAL ISCHEMIA Myocardial cells require oxygen and other nutrients to function. Oxygenated blood is supplied by the coronary arteries. If severe narrowing or complete blockage of a coronary artery causes the blood flow to become inadequate, ischemia of the heart muscle develops. Ischemia means literally “to hold back blood.” Myocardial ischemia may occur transiently. For example, patients ...

background: dietary risk factors constitute some of the leading risk factors for cardiovascular disease in iran. the current study reports the burden of ischemic heart disease (ihd) attributable to a low omega-3 fatty acids intake in iran using the data of the global burden of disease (gbd) study 2010. methods: we used data on iran for the years 1990, 2005, and 2010 derived from the gbd study c...

objective: although coronary artery disease (cad) is the leading cause of death in type 2 diabetic patients, it is frequently asymptomatic. myocardial perfusion imaging (mpi) is reported to show ischemia in a significant number of asymptomatic diabetic patients. we studied the prevalence and severity of myocardial perfusion defects in asymptomatic diabetic patients and its clinical impact. meth...

The Role of Uric Acid to HDL Cholesterol Ratio in Predicting Myocardial Ischemia Perfusion Scintigraphy Diabetic Patients
 Abstract
 Objective: Diabetes Mellitus (DM) is a significant risk factor for cardiovascular diseases, particularly myocardial ischemia. Both diabetes mellitus type 2 and conditions are characterized by high burden inflammation. uric High-Density Lipoprotein choles...

BACKGROUND The heart is a tumor necrosis factor-alpha (TNF-alpha)-producing organ. Recent basic experimental and clinical evidence suggests that TNF-alpha is an important mediator of myocardial injury during acute myocardial infarction, chronic heart failure, cardiac allograft rejection, and cardiopulmonary bypass operations. Although it is known that the myocardium itself is capable of produci...

In the current study, effects of acute short term administration of fructose on cardiac arrhythmias and myocardial infarction size following ischemia/reperfusion were investigated in isolated rat heart. The hearts were subjected to 30 min zero flow global ischemia followed by 120 min reperfusion. In the control group, the hearts were perfused by normal drug free Krebs-Henseleit (K/H) solution t...

Background/Aim. Ischemic heart disease is the major cause of morbidity and mortality in the world as well as in our country. Ischemic heart disease has the multifactorial origin and the presence of several risk factors increases the risk of myocardial ischemia. The aim of the study was to evaluate the frequency and characteristics of myocardial ischemia in asymptomatic subjects with two or more...

Clinical studies have reported that the incidence and severity of myocardial infarction is significantly greater in diabetics compared with nondiabetics after correction for all other risk factors. The majority of studies investigating the pathophysiology of myocardial ischemia-reperfusion injury have focused on otherwise healthy animals. At present, there is a paucity of experimental investiga...