INTRODUCTION Osteoporosis is a major public health problem leading to morbidity and mortality in many individuals. Treatment for osteoporosis has generally relied on mechanisms that decrease osteoclastic bone resorption. This review outlines new evidence that the cholesterol synthetic pathway may be important in bone metabolism and that 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase ...

Three cases of periarteritis nodosa are reported with subperiosteal new bone formation. Two patients have been followed for over five years, the third for only six months. The vascular changes were predominantly found in the smaller vessels, the necrosis and elastin destruction was less than that usually found at necropsy. The radiological follow-up of one case demonsfrated ossification and hea...

Bone is a hierarchically structured composite material which, in addition to its obvious biological value, has been well studied by the materials engineering community because of its unique structure and mechanical properties. This article will review the existing bone literature, with emphasis on the prevailing theories regarding bone formation and structure, which lay the groundwork for propo...

objective: alveolar ridge preservation in patients with inadequate bone volume is one treatment option for successful implant placement and can be done by using bone graft materials. on the other hand, ceno bone has been recently produced by hamanand saz baft kish co. as a bone bioimplant of allograft origin. this study aimed to assess the clinical, histologic and histomorphometric results of b...

reconstruction methods are an essential prerequisite for functional rehabilitation of the stomatognathic system. plasma rich in growth factors (prgf) offers a new and potentially useful adjunct to bone substitute materials in bone reconstructive surgery. this study was carried out to investigate the influence of prgf and fibrin membrane on regeneration of bony defects with and without deprotein...