......................................................................................................................... 2 Acknowledgements ........................................................................................................ 3 1.0 Introduction .............................................................................................................. 4 1.1 Aims and Object...

INTRODUCTION Fragile X syndrome is a well-recognised cause of developmental delay in males and to a lesser extent females. The aim of the present study was to present a detailed cognitive and behaviour analysis of the core attention impairments frequently associated with fragile X. PATIENTS AND METHODS Two complementary studies were conducted. Study 1 examined the severity and range of behavi...

Fragile sites are heritable specific chromosome loci that exhibit an increased frequency of gaps, poor staining, constrictions or breaks when chromosomes are exposed to partial DNA replication inhibition. They constitute areas of chromatin that fail to compact during mitosis. They are classified as rare or common depending on their frequency within the population and are further subdivided on t...

Fragile sites consist of isochromatid chromosome breaks which take place at specific sites along a chromosome and segregate as simple Mendelian traits.1 2 While the Xq28 fragile site is regarded as a marker for X linked mental retardation, the fragile sites on autosomes are regarded as normal uncommon variants. The present case supports the idea that the presence of fragile sites may constitute...

The non-fragile guaranteed controller design problem for an interval system and a given cost function is discussed. A sufficient condition is established such that the closed-loop system stability and cost function is guaranteed to be no more than a certain upper bound with all admissible uncertainties as well as a controller gain perturbation uncertainty. A modified interval system described b...

This paper deals with the quadratic stabilization of discrete-time LTI systems using state-feedback controllers with bounded coefficients. The controllers are guaranteed to be non-fragile with respect to additive or multiplicative implementation errors. The approach is based on robust-control tools and LMIs. Finally, an example is given in order to illustrate the effectiveness of the approach.

This paper deals with the synchronization control problem for the uncertain chaotic neural networks with randomly occurring uncertainties and randomly occurring control gain fluctuations. By introducing an improved Lyapunov–Krasovskii functional and employing reciprocally convex approach, a delaydependent non-fragile output feedback controller is designed to achieve synchronization with the hel...