Three patients with Christmas disease whose plasma was shown to have a prolonged one-stage prothrombin time with ox brain thromboplastin have been investigated. These patients have an inhibitor for the reaction between factor X, factor VII, and ox brain extract. The abnormal constituent responsible for this inhibitor appears to be factor IX whuch is functionally inactive but antigenically indis...

CH3OH temperature programmed surface reaction (TPSR) spectroscopy was employed to determine the chemical nature of active surface sites for bulk mixed metal oxide catalysts. The CH3OH-TPSR spectra peak temperature, Tp, for model supported metal oxides and bulk, pure metal oxides was found to be sensitive to the specific surface metal oxide as well as its oxidation state. The catalytic activity ...

A soluble specific substance was isolated from Mexican typhus Rickettsia which gave, with Proteus X-19 antiserum and typhus human serum, the same precipitation reactions as the polysaccharides extracted from B. proteus OX-19. The soluble specific substance extracted from Rickettsia and Proteus OX-19 is likely to be of a polysaccharide nature owing to the strong Molisch reactions obtained with s...

Native and oxidized (OX) low-density lipoprotein (LDL) may contribute to the pathogenesis of age-related macular degeneration (AMD). In this study, we investigated the effects of lipoproteins, including n-LDL and OX-LDL, on the expression of inflammation factors, interleukin-6 (IL-6) and interleukin-1β (IL-1β), in vivo and in cultured retinal pigment epithelial (RPE) cells. The potential role o...

BACKGROUND Our earlier studies have demonstrated upregulation of monocyte chemoattractant protein-1 (MCP-1) in NRK52E rat renal epithelial cells by exposure to oxalate (Ox) ions and crystals of calcium oxalate monohydrate (COM) or the brushite (Br) form of calcium phosphate. The upregulation was mediated by reactive oxygen species (ROS). This study was performed to investigate whether NADPH oxi...

The catalytic reduction of SO2 to elemental sulfur by methane was studied over ceria-based catalysts. Both La-doped and undoped ceria were found to catalyze the SO2 reduction by CH4 in the temperature range of 550–750◦C at atmospheric pressure and with feed gases containing a molar ratio of CH4/SO2 = 0.5–3. At temperatures below ∼550◦C, the catalyst surface is capped by SO2. The reaction light-...

Cross talk between oxidized LDL (ox-LDL) and angiotensin II (Ang II) may be relevant in atherosclerosis. In this study, we examined the presence of a specific endothelial receptor for ox-LDL (LOX-1) and Ang II receptors in human coronary artery endothelial cells (HCAECs). In addition, we studied the effect of Ang II on LOX-1 gene and protein expression. LOX-1 was consistently identified in HCAE...

Pyranose 2-oxidase (P2O) from Trametes multicolor is a flavoprotein oxidase that catalyzes the oxidation of aldopyranoses by molecular oxygen to yield the corresponding 2-keto-aldoses and hydrogen peroxide. P2O is the first enzyme in the class of flavoprotein oxidases, for which a C4a-hydroperoxy-flavin adenine dinucleotide (FAD) intermediate has been detected during the oxidative half-reaction...

The catalytic reduction of SO2 to elemental sulfur by CO or CH4 over ceria-based catalysts under demanding operating conditions is reported in this paper. Cuor Ni-containing ceria catalysts have been shown before to be highly active and selective for SO2 reduction by CO in dry gas streams or in the presence of low amounts of H2O. In this work, the activity/selectivity of 10 at.%La-doped ceria, ...