Synadenium umbellatum Pax., popularly known in Brazil as "cola-nota," "avelós," "cancerola," and "milagrosa", is a plant species used in folk medicine for the treatment of inflammation, pain, and several diseases. This study aimed to investigate the antinociceptive and anti-inflammatory activities of the ethanolic extract from Synadenium umbellatum Pax. leaves (EES) and its hexane (HF), chlorof...

conclusions the present data confirmed systemic and topical anti-inflammatory effects of stachys pilifera which is comparable to indomethacin. results acute toxicity study of the extract showed that no rats were killed at 5000 mg/kg (ld50 > 5000 mg/kg). the extract (100 and 200  mg/ kg) significantly suppressed carrageenan-induced paw edema 1, 2, 3, and 4  hours after carrageenan challenge in c...

Licochalcone A was isolated from the roots of Glycyrrhiza inflata and evaluated for its anti-inflammatory activity in xylene-induced mice ear edema and carrageenan-induced paw edema tests. At the same time, the inhibition of prostaglandin biosynthesis by licochalcone A was also studied in lipopolysaccharide (LPS)-induced mouse macrophage cells. At 5 mg/ ear, licochalcone A showed remarkable eff...

There are some evidences regarding anti-allergic and anti-inflammatory effects of Licorice common in traditional medicine and its usefulness in Diabetes mellitus and Diabetes insipidus and its stimulatory effect on admeocortical gland. This medicinal plant contains glycyrrhizin, sterogenic substances, cumarins, flavonoids, sterols, choline, asparagine and glaberin. Glycyrrhizin and glaberin hav...

Anti-inflammatory effects of the aqueous extract of Hibiscus taiwanensis (AHT) were used in lipopolysaccharide (LPS-)stimulated mouse macrophage RAW264.7 cells and carrageenan (Carr-)induced mouse paw edema model. When RAW264.7 macrophages were treated with AHT together with LPS, a concentration-dependent inhibition of nitric oxide (NO), tumor necrosis factor (TNF-α), and prostaglandin E2 (PGE(...

This study investigated the analgesic and anti-inflammatory effects of Crinum asiaticum (Amaryllidaceae) leaf ethanolic extract. Analgesic effect was investigated in acetic acid induced writhing model and formalin induced licking model in swiss albino mice. Anti-inflammatory effect was conducted in carrageenan-induced paw edema model of albino rat. Data were analyzed by one-way analysis of vari...

Preclinical Research The aim of this study was to evaluate the efficacy of multiple applications of S(+)-flurbiprofen plaster (SFPP), a novel Nonsteroidal anti-inflammatory drug (NSAID) patch, for the alleviation of inflammatory pain and edema in rat adjuvant-induced arthritis (AIA) model as compared to other NSAID patches. The AIA model was induced by the injection of Mycobacterium butyricum a...

Plan: Anti-inflammatory evaluation of abyssinone V-4’-methyl ether. Prologue: The anti-inflammatory activity of abyssinone V-4'-methyl ether, a natural prenylated flavonoid isolated from the bark of Erythrina droogmansiana (Leguminosae) was evaluated using acute and chronic inflammation models in vivo namely carrageenan-induced paw edema in rats, xylene induced-ear edema in mice and cotton pell...

In this study the anti-inflammatory activity of ethanolic extract of Cynanchum acutum was evaluated. Cynanchum acutum has a large history of herbal use because of pharmaceutical characteristics and the medicinal values of the Cynanchum acutum have been mentioned in ancient literature as useful in disorders. The effects of ethanolic extracts of Cynanchum acutum were studied on carrageen an induc...